Pralatrexate and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Pralatrexate (pralatrexate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Gemcitabine, and have Peripheral t-cell lymphoma unspecified.

The phase IV clinical study analyzes which people have Fatigue when taking Pralatrexate. It is created by eHealthMe based on reports of 230 people who have side effects when taking Pralatrexate from the FDA, and is updated regularly.

What is Pralatrexate?

Pralatrexate has active ingredients of pralatrexate. eHealthMe is studying from 231 Pralatrexate users. Check the latest studies of Pralatrexate.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,380 conditions by eHealthMe. Check the latest studies of Fatigue.



On Jul, 26, 2026

230 people reported to have side effects when taking Pralatrexate.
Among them, 22 people (9.57%) have Fatigue.

Could Pralatrexate cause Fatigue?

Among these 22 people:

How long have people been on Pralatrexate when they have Fatigue? *

  • < 1 month: 61.54 %
  • 1 - 6 months: 23.08 %
  • 6 - 12 months: 7.69 %
  • 1 - 2 years: 7.69 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fatigue when taking Pralatrexate? *

  • female: 70 %
  • male: 30 %

What is the age of people who have Fatigue when taking Pralatrexate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 30 %
  • 60+: 60 %

What are other drugs people take besides Pralatrexate? *

  1. Gemcitabine: 8 people, 36.36%
  2. Folic Acid: 5 people, 22.73%
  3. Romidepsin: 4 people, 18.18%
  4. Dronabinol: 3 people, 13.64%
  5. Oxycontin: 3 people, 13.64%
  6. Prednisone: 3 people, 13.64%
  7. Methocarbamol: 3 people, 13.64%
  8. Cyclophosphamide: 2 people, 9.09%
  9. Bisacodyl: 2 people, 9.09%
  10. Potassium Chloride: 2 people, 9.09%

What are other side effects people have besides Fatigue? *

  1. Dyspnea (difficult or laboured breathing): 9 people, 40.91%
  2. Weakness: 9 people, 40.91%
  3. Fever: 8 people, 36.36%
  4. Nausea (feeling of having an urge to vomit): 8 people, 36.36%
  5. Dehydration (dryness resulting from the removal of water): 7 people, 31.82%
  6. Thrombocytopenia (decrease of platelets in blood): 7 people, 31.82%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 31.82%
  8. Anaemia (lack of blood): 6 people, 27.27%
  9. Malaise (a feeling of general discomfort or uneasiness): 5 people, 22.73%
  10. Bacteraemia (presence of bacteria in the blood): 4 people, 18.18%

What are the existing conditions these people have? *

  1. Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 5 people, 22.73%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 13.64%
  3. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 3 people, 13.64%
  4. Bladder Cancer: 2 people, 9.09%
  5. Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 1 person, 4.55%
  6. Ovarian Cancer (cancer of ovary): 1 person, 4.55%
  7. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 4.55%
  8. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 4.55%
  9. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Pralatrexate and have Fatigue?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pralatrexate:

Fatigue treatments and more:

How severe was Fatigue and when was it recovered:

Expand to all the drugs that have ingredients of pralatrexate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pralatrexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Browse all the conditions that are associated with Fatigue:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pralatrexate (the active ingredients of Pralatrexate) and Pralatrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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