Pramine and Gingival disorder - a phase IV clinical study of FDA data

Summary:

Gingival disorder is reported as a side effect among people who take Pramine (imipramine hydrochloride), especially for people who are female, 50-59 old, also take Levaquin, and have Neoplasm malignant.

The phase IV clinical study analyzes which people have Gingival disorder when taking Pramine. It is created by eHealthMe based on reports of 7,187 people who have side effects when taking Pramine from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Gingival disorder?

Gingival disorder (gum disease) is found to be associated with 669 drugs and 568 conditions by eHealthMe. Check the latest studies of Gingival disorder.

On Jul, 10, 2026

7,187 people reported to have side effects when taking Pramine.
Among them, 13 people (0.18%) have Gingival disorder.

Among these 13 people:

What is the gender of people who have Gingival disorder when taking Pramine? *

female: 75 %
male: 25 %

What is the age of people who have Gingival disorder when taking Pramine? *

What are other drugs people take besides Pramine? *

What are other side effects people have besides Gingival disorder? *

Fatigue (feeling of tiredness): 11 people, 84.62%
Pain: 10 people, 76.92%
Swelling: 10 people, 76.92%
Pneumonia: 8 people, 61.54%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 8 people, 61.54%
Pain In Jaw: 8 people, 61.54%
Thrombocytopenia (decrease of platelets in blood): 8 people, 61.54%
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth): 8 people, 61.54%
Urinary Tract Infection: 8 people, 61.54%
Osteonecrosis Of Jaw (death of bone of jaw): 7 people, 53.85%

What are the existing conditions these people have? *

Hypercalcaemia (elevated calcium (ca+) level in the blood): 5 people, 38.46%
Osteoporosis (bones weak and more likely to break): 5 people, 38.46%
Neoplasm Malignant (cancer tumour): 5 people, 38.46%
Metastases To Bone (cancer spreads to bone): 2 people, 15.38%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.69%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 1 person, 7.69%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.69%
Depression: 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Pramine and have Gingival disorder?

- Check whether Gingival disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pramine:

Pramine (7,461 reports)

Browse all side effects of Pramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingival disorder:

Gingival disorder (669 drugs)

Browse all the conditions that are associated with Gingival disorder:

Gingival disorder (568 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on imipramine hydrochloride (the active ingredients of Pramine) and Pramine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.