Precedex and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Precedex (dexmedetomidine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Pantoprazole, and have Non-small cell lung cancer metastatic.

The phase IV clinical study analyzes which people have Fatigue when taking Precedex. It is created by eHealthMe based on reports of 998 people who have side effects when taking Precedex from the FDA, and is updated regularly.

What is Precedex?

Precedex has active ingredients of dexmedetomidine. eHealthMe is studying from 1,007 Precedex users. Check the latest studies of Precedex.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,026 drugs and 6,379 conditions by eHealthMe. Check the latest studies of Fatigue.



On Jul, 16, 2026

998 people reported to have side effects when taking Precedex.
Among them, 20 people (2.0%) have Fatigue.

Could Precedex cause Fatigue?

Among these 20 people:

How long have people been on Precedex when they have Fatigue? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fatigue when taking Precedex? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Fatigue when taking Precedex? *

  • 0-1: 0.0 %
  • 2-9: 20 %
  • 10-19: 20 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 10 %
  • 60+: 40 %

What are other drugs people take besides Precedex? *

  1. Zometa: 10 people, 50.00%
  2. Alprazolam: 10 people, 50.00%
  3. Pantoprazole: 10 people, 50.00%
  4. Lorazepam: 9 people, 45.00%
  5. Flexeril: 8 people, 40.00%
  6. Motrin: 8 people, 40.00%
  7. Zolpidem: 8 people, 40.00%
  8. Xanax: 7 people, 35.00%
  9. Nasacort: 7 people, 35.00%
  10. Lortab: 7 people, 35.00%

What are other side effects people have besides Fatigue? *

  1. Dyspnea (difficult or laboured breathing): 16 people, 80.00%
  2. Hypotension (abnormally low blood pressure): 13 people, 65.00%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 13 people, 65.00%
  4. Weakness: 12 people, 60.00%
  5. Anaemia (lack of blood): 11 people, 55.00%
  6. Intervertebral Disc Protrusion (spinal disc protrusion): 10 people, 50.00%
  7. Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration): 10 people, 50.00%
  8. Osteolysis (dissolution of bone): 10 people, 50.00%
  9. Emotional Distress: 10 people, 50.00%
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 10 people, 50.00%

What are the existing conditions these people have? *

  1. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 8 people, 40.00%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 30.00%
  3. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 15.00%
  4. Constipation: 3 people, 15.00%
  5. Allergic Rhinitis: 2 people, 10.00%
  6. Procedural Pain: 2 people, 10.00%
  7. Procedural Nausea: 2 people, 10.00%
  8. Post Procedural Constipation: 2 people, 10.00%
  9. Anaesthesia: 2 people, 10.00%
  10. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Precedex and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Precedex:

Fatigue treatments and more:

How severe was Fatigue and when was it recovered:

Expand to all the drugs that have ingredients of dexmedetomidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Precedex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Browse all the conditions that are associated with Fatigue:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dexmedetomidine (the active ingredients of Precedex) and Precedex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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