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Prednisone and Distributive shock - a phase IV clinical study of FDA data

Summary:

Distributive shock is reported as a side effect among people who take Prednisone (prednisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tacrolimus, and have Clostridium difficile colitis.

The phase IV clinical study analyzes which people have Distributive shock when taking Prednisone. It is created by eHealthMe based on reports of 628,814 people who have side effects when taking Prednisone from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Distributive shock?

Distributive shock (hock caused by poor distribution of the blood flow) is found to be associated with 116 drugs and 123 conditions by eHealthMe. Check the latest studies of Distributive shock.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

628,814 people reported to have side effects when taking Prednisone.
Among them, 57 people (0.01%) have Distributive shock.

Could Prednisone cause Distributive shock?

Among these 57 people:

How long have people been on Prednisone when they have Distributive shock? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Distributive shock when taking Prednisone? *

  • female: 53.57 %
  • male: 46.43 %

What is the age of people who have Distributive shock when taking Prednisone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.36 %
  • 50-59: 8.93 %
  • 60+: 85.71 %

What are other drugs people take besides Prednisone? *

  1. Tacrolimus: 45 people, 78.95%
  2. Mycophenolic Acid: 35 people, 61.40%
  3. Pyrazinamide: 24 people, 42.11%
  4. Rifampin: 23 people, 40.35%
  5. Isoniazid: 23 people, 40.35%
  6. Metronidazole: 22 people, 38.60%
  7. Metformin: 20 people, 35.09%
  8. Amlodipine: 19 people, 33.33%
  9. Hydroxyzine: 18 people, 31.58%
  10. Lamivudine: 18 people, 31.58%

What are other side effects people have besides Distributive shock? *

  1. Pancreatitis Haemorrhagic (inflammation of pancreas with bleeding): 28 people, 49.12%
  2. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 24 people, 42.11%
  3. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 19 people, 33.33%
  4. Pleural Effusion (water on the lungs): 19 people, 33.33%
  5. Cardiac Arrest: 18 people, 31.58%
  6. Lactic Acidosis (low ph in body tissues): 18 people, 31.58%
  7. Hypotension (abnormally low blood pressure): 18 people, 31.58%
  8. Bradyarrhythmia (heart slowness): 18 people, 31.58%
  9. Hyperkalemia (damage to or disease of the kidney): 18 people, 31.58%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 18 people, 31.58%

What are the existing conditions these people have? *

  1. Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 23 people, 40.35%
  2. Disseminated Tuberculosis: 22 people, 38.60%
  3. Dyspnea (difficult or laboured breathing): 16 people, 28.07%
  4. Mastitis Bacterial (bacterial infection of breast): 12 people, 21.05%
  5. Type 1 Diabetes: 8 people, 14.04%
  6. Breast Infection: 6 people, 10.53%
  7. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 8.77%
  8. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 4 people, 7.02%
  9. Infectious Pleural Effusion (infectious fluid in the lung): 3 people, 5.26%
  10. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and have Distributive shock?

- Check whether Distributive shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisone:

Distributive shock treatments and more:

How severe was Distributive shock and when was it recovered:

Expand to all the drugs that have ingredients of prednisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Distributive shock:

Browse all the conditions that are associated with Distributive shock:

How the study uses the data?

The study uses data from the FDA. It is based on prednisone (the active ingredients of Prednisone) and Prednisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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