Prednisone and Ileal perforation - a phase IV clinical study of FDA data

Summary:

Ileal perforation is reported as a side effect among people who take Prednisone (prednisone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Accutane, and have Crohn's disease.

The phase IV clinical study analyzes which people have Ileal perforation when taking Prednisone. It is created by eHealthMe based on reports of 628,814 people who have side effects when taking Prednisone from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Ileal perforation?

Ileal perforation is found to be associated with 99 drugs and 258 conditions by eHealthMe. Check the latest studies of Ileal perforation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

628,814 people reported to have side effects when taking Prednisone.
Among them, 69 people (0.01%) have Ileal perforation.

Could Prednisone cause Ileal perforation?

Among these 69 people:

How long have people been on Prednisone when they have Ileal perforation? *

What is the gender of people who have Ileal perforation when taking Prednisone? *

female: 29.69 %
male: 70.31 %

What is the age of people who have Ileal perforation when taking Prednisone? *

What are other drugs people take besides Prednisone? *

What are other side effects people have besides Ileal perforation? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 24.64%
Inflammatory Bowel Disease: 12 people, 17.39%
Sepsis (a severe blood infection that can lead to organ failure and death): 10 people, 14.49%
Abdominal Pain: 10 people, 14.49%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 13.04%
Vitamin B12 Deficiency: 9 people, 13.04%
Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 9 people, 13.04%
Gastroenteritis (inflammation of stomach and intestine): 9 people, 13.04%
Gastric Ulcer (stomach ulcer): 9 people, 13.04%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9 people, 13.04%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 19 people, 27.54%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 8.70%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 4 people, 5.80%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 2.90%
Colitis (inflammation of colon): 2 people, 2.90%
Pigmentation Disorder (disturbances of human skin colour): 2 people, 2.90%
Gastritis (inflammation of stomach): 2 people, 2.90%
Constipation: 2 people, 2.90%
Iron Deficiency Anaemia: 2 people, 2.90%
Lymphoma (cancer that begins in immune system cells): 2 people, 2.90%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and have Ileal perforation?

- Check whether Ileal perforation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisone:

Prednisone (636,827 reports)

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ileal perforation:

Ileal perforation (99 drugs)

Browse all the conditions that are associated with Ileal perforation:

Ileal perforation (258 conditions)

Related publications that referenced our studies

Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on prednisone (the active ingredients of Prednisone) and Prednisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.