Prednisone and Iron overload - a phase IV clinical study of FDA data

Summary:

Iron overload is reported as a side effect among people who take Prednisone (prednisone), especially for people who are male, 60+ old, also take Soliris, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Iron overload when taking Prednisone. It is created by eHealthMe based on reports of 628,814 people who have side effects when taking Prednisone from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Iron overload?

Iron overload is found to be associated with 191 drugs and 312 conditions by eHealthMe. Check the latest studies of Iron overload.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

628,814 people reported to have side effects when taking Prednisone.
Among them, 68 people (0.01%) have Iron overload.

Could Prednisone cause Iron overload?

Among these 68 people:

What is the gender of people who have Iron overload when taking Prednisone? *

  • female: 45.61 %
  • male: 54.39 %

What is the age of people who have Iron overload when taking Prednisone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 20.83 %
  • 20-29: 4.17 %
  • 30-39: 0.0 %
  • 40-49: 6.25 %
  • 50-59: 2.08 %
  • 60+: 66.67 %

What are other drugs people take besides Prednisone? *

  1. Soliris: 19 people, 27.94%
  2. Exjade: 12 people, 17.65%
  3. Aspirin: 12 people, 17.65%
  4. Jakafi: 10 people, 14.71%
  5. Omeprazole: 9 people, 13.24%
  6. Lumigan: 8 people, 11.76%
  7. Lasix: 8 people, 11.76%
  8. Folic Acid: 8 people, 11.76%
  9. Revlimid: 8 people, 11.76%
  10. Methotrexate: 7 people, 10.29%

What are other side effects people have besides Iron overload? *

  1. Fatigue (feeling of tiredness): 25 people, 36.76%
  2. Dyspnea (difficult or laboured breathing): 19 people, 27.94%
  3. Anaemia (lack of blood): 18 people, 26.47%
  4. Thrombocytopenia (decrease of platelets in blood): 12 people, 17.65%
  5. Weakness: 12 people, 17.65%
  6. Acute Kidney Failure: 11 people, 16.18%
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 10 people, 14.71%
  8. Hepatic Failure (liver failure): 9 people, 13.24%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 13.24%
  10. Pleural Effusion (water on the lungs): 8 people, 11.76%

What are the existing conditions these people have? *

  1. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 19 people, 27.94%
  2. Pain: 8 people, 11.76%
  3. Primary Myelofibrosis (primary disorder of the bone marrow): 8 people, 11.76%
  4. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 6 people, 8.82%
  5. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 8.82%
  6. Itching: 5 people, 7.35%
  7. Nausea (feeling of having an urge to vomit): 5 people, 7.35%
  8. Aplastic Anemia: 4 people, 5.88%
  9. Nephrogenic Anaemia (anaemia due to kidney disease): 4 people, 5.88%
  10. Osteoporosis (bones weak and more likely to break): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and have Iron overload?

- Check whether Iron overload is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisone:

Iron overload treatments and more:

How severe was Iron overload and when was it recovered:

Expand to all the drugs that have ingredients of prednisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Iron overload:

Browse all the conditions that are associated with Iron overload:


How the study uses the data?

The study uses data from the FDA. It is based on prednisone (the active ingredients of Prednisone) and Prednisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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