Pregabalin and Hydrocephalus - a phase IV clinical study of FDA data

Summary:

Hydrocephalus is reported as a side effect among people who take Pregabalin (pregabalin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Naltrexone, and have Thyroid diseases.

The phase IV clinical study analyzes which people have Hydrocephalus when taking Pregabalin. It is created by eHealthMe based on reports of 73,056 people who have side effects when taking Pregabalin from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.

What is Hydrocephalus?

Hydrocephalus (water on the brain) is found to be associated with 764 drugs and 1,367 conditions by eHealthMe. Check the latest studies of Hydrocephalus.

On Apr, 23, 2026

73,056 people reported to have side effects when taking Pregabalin.
Among them, 27 people (0.04%) have Hydrocephalus.

Among these 27 people:

How long have people been on Pregabalin when they have Hydrocephalus? *

What is the gender of people who have Hydrocephalus when taking Pregabalin? *

female: 56 %
male: 44 %

What is the age of people who have Hydrocephalus when taking Pregabalin? *

What are other drugs people take besides Pregabalin? *

What are other side effects people have besides Hydrocephalus? *

Stress And Anxiety: 9 people, 33.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 33.33%
Androgen Deficiency: 8 people, 29.63%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 8 people, 29.63%
Growth Hormone Deficiency: 8 people, 29.63%
Pituitary Cyst: 8 people, 29.63%
Head Injury: 8 people, 29.63%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 29.63%
Headache (pain in head): 6 people, 22.22%
Gait Disturbance: 6 people, 22.22%

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 29.63%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 29.63%
Thyroid Diseases: 8 people, 29.63%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 11.11%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 11.11%
Nausea (feeling of having an urge to vomit): 2 people, 7.41%
Headache (pain in head): 2 people, 7.41%
Hypokalemia (low potassium): 2 people, 7.41%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Pregabalin and have Hydrocephalus?

- Check whether Hydrocephalus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pregabalin:

Pregabalin (74,069 reports)

Hydrocephalus treatments and more:

Hydrocephalus (6,876 reports)

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hydrocephalus:

Hydrocephalus (764 drugs)

Browse all the conditions that are associated with Hydrocephalus:

Hydrocephalus (1,367 conditions)

Related publications that referenced our studies

de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Pregabalin) and Pregabalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.