Pregabalin and Onychoclasis - a phase IV clinical study of FDA data
Summary:
Onychoclasis is reported as a side effect among people who take Pregabalin (pregabalin), especially for people who are female, 60+ old, also take Ibuprofen, and have Reflux gastritis.
The phase IV clinical study analyzes which people have Onychoclasis when taking Pregabalin. It is created by eHealthMe based on reports of 73,056 people who have side effects when taking Pregabalin from the FDA, and is updated regularly.
What is Pregabalin?
Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.
What is Onychoclasis?
Onychoclasis (breaking of the nails) is found to be associated with 616 drugs and 607 conditions by eHealthMe. Check the latest studies of Onychoclasis.
73,056 people reported to have side effects when taking Pregabalin.
Among them, 33 people (0.05%) have Onychoclasis.

Among these 33 people:
What is the gender of people who have Onychoclasis when taking Pregabalin? *
- female: 87.5 %
- male: 12.5 %
What is the age of people who have Onychoclasis when taking Pregabalin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 3.7 %
- 50-59: 29.63 %
- 60+: 66.67 %
What are other drugs people take besides Pregabalin? *
- Naproxen: 6 people, 18.18%
- Ibuprofen: 6 people, 18.18%
- Lonsurf: 5 people, 15.15%
- Bisoprolol Fumarate: 5 people, 15.15%
- Diazepam: 5 people, 15.15%
- Felodipine: 5 people, 15.15%
- Omeprazole: 5 people, 15.15%
- Xeljanz: 4 people, 12.12%
- Arava: 4 people, 12.12%
- Celebrex: 4 people, 12.12%
What are other side effects people have besides Onychoclasis? *
- Fatigue (feeling of tiredness): 17 people, 51.52%
- Drowsiness: 12 people, 36.36%
- Dizziness: 12 people, 36.36%
- Balance Disorder: 12 people, 36.36%
- Headache (pain in head): 10 people, 30.30%
- Memory Loss: 10 people, 30.30%
- Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 9 people, 27.27%
- Muscle Spasms (muscle contraction): 9 people, 27.27%
- Abdominal Pain: 9 people, 27.27%
- Feeling Abnormal: 9 people, 27.27%
What are the existing conditions these people have? *
- Hypoaesthesia (reduced sense of touch or sensation): 5 people, 15.15%
- Pain In Extremity: 5 people, 15.15%
- High Blood Cholesterol: 5 people, 15.15%
- High Blood Pressure: 5 people, 15.15%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 5 people, 15.15%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 15.15%
- Muscle Spasms (muscle contraction): 5 people, 15.15%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 15.15%
- Migraine (headache): 5 people, 15.15%
- Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 5 people, 15.15%
* Approximation only. Some reports may have incomplete information.
Do you take Pregabalin and have Onychoclasis?
- Check whether Onychoclasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Pregabalin:
- Pregabalin (74,069 reports)
Onychoclasis treatments and more:
- Onychoclasis (7,925 reports)
How severe was Onychoclasis and when was it recovered:
Expand to all the drugs that have ingredients of pregabalin:
- Onychoclasis and drugs with ingredients of pregabalin (162 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pregabalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Onychoclasis:
- Onychoclasis (616 drugs)
Browse all the conditions that are associated with Onychoclasis:
- Onychoclasis (607 conditions)
Related publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on pregabalin (the active ingredients of Pregabalin) and Pregabalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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