Premarin and Malabsorption - a phase IV clinical study of FDA data

Summary:

Malabsorption is reported as a side effect among people who take Premarin (estrogens, conjugated), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Synthroid, and have High blood pressure.

The phase IV clinical study analyzes which people have Malabsorption when taking Premarin. It is created by eHealthMe based on reports of 98,531 people who have side effects when taking Premarin from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,629 Premarin users. Check the latest studies of Premarin.

What is Malabsorption?

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract) is found to be associated with 757 drugs and 1,080 conditions by eHealthMe. Check the latest studies of Malabsorption.

On Oct, 07, 2025

98,531 people reported to have side effects when taking Premarin.
Among them, 118 people (0.12%) have Malabsorption.

Among these 118 people:

How long have people been on Premarin when they have Malabsorption? *

What is the gender of people who have Malabsorption when taking Premarin? *

female: 96.97 %
male: 3.03 %

What is the age of people who have Malabsorption when taking Premarin? *

What are other drugs people take besides Premarin? *

What are other side effects people have besides Malabsorption? *

Urinary Tract Infection: 26 people, 22.03%
Pain: 24 people, 20.34%
Fall: 23 people, 19.49%
Weight Decreased: 23 people, 19.49%
Drug Ineffective: 21 people, 17.80%
Nausea (feeling of having an urge to vomit): 20 people, 16.95%
Hair Loss: 19 people, 16.10%
Diarrhea: 19 people, 16.10%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 15.25%
High Blood Pressure: 18 people, 15.25%

What are the existing conditions these people have? *

High Blood Pressure: 42 people, 35.59%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 19 people, 16.10%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 16 people, 13.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 12.71%
Muscle Spasms (muscle contraction): 14 people, 11.86%
Rashes (redness): 13 people, 11.02%
Vulvovaginal Dryness: 13 people, 11.02%
Vulvovaginal Pain: 13 people, 11.02%
Vulvovaginal Discomfort: 13 people, 11.02%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 13 people, 11.02%

* Approximation only. Some reports may have incomplete information.

Do you take Premarin and have Malabsorption?

- Check whether Malabsorption is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Premarin:

Premarin (99,629 reports)

Malabsorption treatments and more:

Malabsorption (8,910 reports)

Browse all side effects of Premarin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Malabsorption:

Browse all the drugs that are associated with Malabsorption:

Malabsorption (757 drugs)

Common conditions associated with Malabsorption:

Htn: 2,367 reports
Crohns disease: 330 reports
Pain: 250 reports
Alternative medicine - pain relief: 248 reports
Gastroesophageal reflux disease: 234 reports
Blood triglycerides abnormal: 220 reports
Depression: 216 reports
Acupuncture and pain: 201 reports
Diabetes mellitus: 193 reports
Dm: 190 reports

Browse all the conditions that are associated with Malabsorption:

Malabsorption (1,080 conditions)

Drugs similar to Premarin and Malabsorption :

Estradiol side effect: Malabsorption

How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated (the active ingredients of Premarin) and Premarin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.