Premarin and Ovarian mass - a phase IV clinical study of FDA data

Summary:

Ovarian mass is reported as a side effect among people who take Premarin (estrogens, conjugated), especially for people who are 50-59 old, have been taking the drug for 2 - 5 years also take Zometa, and have High blood pressure.

The phase IV clinical study analyzes which people have Ovarian mass when taking Premarin. It is created by eHealthMe based on reports of 98,531 people who have side effects when taking Premarin from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

What is Ovarian mass?

Ovarian mass (mass in ovary) is found to be associated with 201 drugs and 240 conditions by eHealthMe. Check the latest studies of Ovarian mass.



On Jul, 25, 2026

98,531 people reported to have side effects when taking Premarin.
Among them, 30 people (0.03%) have Ovarian mass.

Could Premarin cause Ovarian mass?

Among these 30 people:

How long have people been on Premarin when they have Ovarian mass? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Ovarian mass when taking Premarin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.41 %
  • 50-59: 59.26 %
  • 60+: 33.33 %

What are other drugs people take besides Premarin? *

  1. Aredia: 13 people, 43.33%
  2. Lipitor: 13 people, 43.33%
  3. Xanax: 13 people, 43.33%
  4. Hydrochlorothiazide: 13 people, 43.33%
  5. Zometa: 13 people, 43.33%
  6. Anastrozole: 12 people, 40.00%
  7. Percocet: 12 people, 40.00%
  8. Celexa: 12 people, 40.00%
  9. Taxol: 12 people, 40.00%
  10. Arimidex: 11 people, 36.67%

What are other side effects people have besides Ovarian mass? *

  1. High Blood Pressure: 21 people, 70.00%
  2. Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 15 people, 50.00%
  3. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 14 people, 46.67%
  4. Constipation: 14 people, 46.67%
  5. Chest Pain: 14 people, 46.67%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 14 people, 46.67%
  7. X-Ray Abnormal: 13 people, 43.33%
  8. Oedema Peripheral (superficial swelling): 13 people, 43.33%
  9. Pneumonia: 13 people, 43.33%
  10. Pleural Effusion (water on the lungs): 13 people, 43.33%

What are the existing conditions these people have? *

  1. Joint Pain: 5 people, 16.67%
  2. High Blood Pressure: 5 people, 16.67%
  3. Metastatic Carcinoid Tumor: 4 people, 13.33%
  4. Gastric Disorder (disease of stomach): 3 people, 10.00%
  5. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 10.00%
  6. Blood Pressure Abnormal: 3 people, 10.00%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 10.00%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.67%
  9. Stable Angina (a constant chest pain): 1 person, 3.33%
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Premarin and have Ovarian mass?

- Check whether Ovarian mass is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Premarin:

Ovarian mass treatments and more:

How severe was Ovarian mass and when was it recovered:

Expand to all the drugs that have ingredients of estrogens, conjugated:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Premarin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ovarian mass:

Browse all the conditions that are associated with Ovarian mass:


How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated (the active ingredients of Premarin) and Premarin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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