Premphase and Sinusitis - a phase IV clinical study of FDA data

Summary:

Sinusitis is reported as a side effect among people who take Premphase (estrogens, conjugated; medroxyprogesterone acetate), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Lantus, and have Metastases to bone.

The phase IV clinical study analyzes which people have Sinusitis when taking Premphase. It is created by eHealthMe based on reports of 2,248 people who have side effects when taking Premphase from the FDA, and is updated regularly.

What is Premphase?

Premphase has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. eHealthMe is studying from 2,262 Premphase users. Check the latest studies of Premphase.

What is Sinusitis?

Sinusitis (inflammation of sinus) is found to be associated with 2,399 drugs and 2,727 conditions by eHealthMe. Check the latest studies of Sinusitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 13, 2026

2,248 people reported to have side effects when taking Premphase.
Among them, 13 people (0.58%) have Sinusitis.

Among these 13 people:

How long have people been on Premphase when they have Sinusitis? *

What is the gender of people who have Sinusitis when taking Premphase? *

female: 100 %
male: 0.0 %

What is the age of people who have Sinusitis when taking Premphase? *

What are other drugs people take besides Premphase? *

What are other side effects people have besides Sinusitis? *

Dizziness: 10 people, 76.92%
Pain: 9 people, 69.23%
High Blood Cholesterol: 9 people, 69.23%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 69.23%
Muscle Spasms (muscle contraction): 9 people, 69.23%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 9 people, 69.23%
Upper Respiratory Tract Infection: 8 people, 61.54%
Cough: 8 people, 61.54%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 7 people, 53.85%
Gastritis (inflammation of stomach): 7 people, 53.85%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 7 people, 53.85%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Premphase and have Sinusitis?

- Check whether Sinusitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Premphase:

Premphase (2,262 reports)

Sinusitis treatments and more:

Sinusitis (153,485 reports)

How severe was Sinusitis and when was it recovered:

Sinusitis in Premphase

Expand to all the drugs that have ingredients of estrogens, conjugated; medroxyprogesterone acetate:

Sinusitis and drugs with ingredients of estrogens, conjugated; medroxyprogesterone acetate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Premphase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinusitis:

Sinusitis (2,399 drugs)

Browse all the conditions that are associated with Sinusitis:

Sinusitis (2,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated; medroxyprogesterone acetate (the active ingredients of Premphase) and Premphase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.