Prempro and Blood thyroid stimulating hormone increased - a phase IV clinical study of FDA data

Summary:

Blood thyroid stimulating hormone increased is reported as a side effect among people who take Prempro (estrogens, conjugated; medroxyprogesterone acetate), especially for people who are female, 50-59 old, also take Combipatch, and have Bone disorder.

The phase IV clinical study analyzes which people have Blood thyroid stimulating hormone increased when taking Prempro. It is created by eHealthMe based on reports of 42,607 people who have side effects when taking Prempro from the FDA, and is updated regularly.

What is Prempro?

Prempro has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause. eHealthMe is studying from 42,950 Prempro users. Check the latest studies of Prempro.

What is Blood thyroid stimulating hormone increased?

Blood thyroid stimulating hormone increased is found to be associated with 675 drugs and 843 conditions by eHealthMe. Check the latest studies of Blood thyroid stimulating hormone increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

42,607 people reported to have side effects when taking Prempro.
Among them, 14 people (0.03%) have Blood thyroid stimulating hormone increased.

Could Prempro cause Blood thyroid stimulating hormone increased?

Among these 14 people:

What is the gender of people who have Blood thyroid stimulating hormone increased when taking Prempro? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Blood thyroid stimulating hormone increased when taking Prempro? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 8.33 %
  • 50-59: 75.0 %
  • 60+: 16.67 %

What are other drugs people take besides Prempro? *

  1. Estraderm: 5 people, 35.71%
  2. Provera: 5 people, 35.71%
  3. Ogen: 5 people, 35.71%
  4. Aygestin: 5 people, 35.71%
  5. Vivelle: 5 people, 35.71%
  6. Premarin: 5 people, 35.71%
  7. Combipatch: 5 people, 35.71%
  8. Estrogenic Substance: 4 people, 28.57%
  9. Synthroid: 3 people, 21.43%
  10. Gilenya: 2 people, 14.29%

What are other side effects people have besides Blood thyroid stimulating hormone increased? *

  1. Fever: 6 people, 42.86%
  2. Stress And Anxiety: 6 people, 42.86%
  3. Hepatic Enzyme Increased: 5 people, 35.71%
  4. Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 5 people, 35.71%
  5. Breast Cancer: 5 people, 35.71%
  6. Oral Pain: 5 people, 35.71%
  7. Depression: 5 people, 35.71%
  8. Breast Disorder: 5 people, 35.71%
  9. Breast Lump (localized swelling that feels different from the surrounding breast tissue): 5 people, 35.71%
  10. Hepatitis (inflammation of the liver): 5 people, 35.71%

What are the existing conditions these people have? *

  1. Vulvovaginal Dryness: 4 people, 28.57%
  2. Hot Flush (sudden feelings of heat): 4 people, 28.57%
  3. Bone Disorder: 4 people, 28.57%
  4. Pain: 2 people, 14.29%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%
  6. High Blood Pressure: 2 people, 14.29%
  7. Thyroiditis Subacute (inflammation of thyroid gland less severe and less durational): 1 person, 7.14%
  8. Nausea (feeling of having an urge to vomit): 1 person, 7.14%
  9. Mitral Valve Prolapse (heart's mitral valve doesn't work well): 1 person, 7.14%
  10. Irritable Bowel Syndrome: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Prempro and have Blood thyroid stimulating hormone increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prempro:

Blood thyroid stimulating hormone increased treatments and more:

How severe was Blood thyroid stimulating hormone increased and when was it recovered:

Expand to all the drugs that have ingredients of estrogens, conjugated; medroxyprogesterone acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prempro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood thyroid stimulating hormone increased:

Browse all the conditions that are associated with Blood thyroid stimulating hormone increased:


How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated; medroxyprogesterone acetate (the active ingredients of Prempro) and Prempro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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