Prilosec otc and Nephrosclerosis - a phase IV clinical study of FDA data

Summary:

Nephrosclerosis is reported as a side effect among people who take Prilosec otc (omeprazole magnesium), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Prevacid, and have High blood pressure.

The phase IV clinical study analyzes which people have Nephrosclerosis when taking Prilosec otc. It is created by eHealthMe based on reports of 37,577 people who have side effects when taking Prilosec otc from the FDA, and is updated regularly.

What is Prilosec otc?

Prilosec otc has active ingredients of omeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 38,394 Prilosec otc users. Check the latest studies of Prilosec otc.

What is Nephrosclerosis?

Nephrosclerosis (hardening of the kidney due to renovascular disease) is found to be associated with 348 drugs and 314 conditions by eHealthMe. Check the latest studies of Nephrosclerosis.



On Jul, 10, 2026

37,577 people reported to have side effects when taking Prilosec otc.
Among them, 64 people (0.17%) have Nephrosclerosis.

Could Prilosec otc cause Nephrosclerosis?

Among these 64 people:

How long have people been on Prilosec otc when they have Nephrosclerosis? *

  • < 1 month: 2.27 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 4.55 %
  • 2 - 5 years: 6.82 %
  • 5 - 10 years: 31.82 %
  • 10+ years: 54.55 %

What is the gender of people who have Nephrosclerosis when taking Prilosec otc? *

  • female: 46.81 %
  • male: 53.19 %

What is the age of people who have Nephrosclerosis when taking Prilosec otc? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.69 %
  • 40-49: 15.38 %
  • 50-59: 23.08 %
  • 60+: 53.85 %

What are other drugs people take besides Prilosec otc? *

  1. Nexium: 53 people, 82.81%
  2. Prevacid: 53 people, 82.81%
  3. Prilosec: 52 people, 81.25%
  4. Prevacid 24 Hr: 48 people, 75.00%
  5. Nexium 24hr: 40 people, 62.50%
  6. Protonix: 24 people, 37.50%
  7. Dexilant: 12 people, 18.75%
  8. Pantoprazole: 9 people, 14.06%
  9. Norvasc: 5 people, 7.81%
  10. Zegerid: 4 people, 6.25%

What are other side effects people have besides Nephrosclerosis? *

  1. Chronic Kidney Disease: 64 people, 100.00%
  2. Acute Kidney Failure: 43 people, 67.19%
  3. Renal Impairment (severely reduced kidney function): 30 people, 46.88%
  4. Nephrogenic Anaemia (anaemia due to kidney disease): 26 people, 40.62%
  5. Nephropathy (damage to or disease of a kidney): 24 people, 37.50%
  6. Diabetic Nephropathy (diabetic kidney disease): 23 people, 35.94%
  7. Hypertensive Nephropathy (hypertensive renal disease): 17 people, 26.56%
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 16 people, 25.00%
  9. Haematuria (presence of blood in urine): 15 people, 23.44%
  10. Renal Injury (kidney injury): 14 people, 21.88%

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 7.81%
  2. Hyperchlorhydria (gastric acid levels are higher in stomach): 3 people, 4.69%
  3. Headache (pain in head): 2 people, 3.12%
  4. Depression: 2 people, 3.12%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.12%
  6. Pain: 2 people, 3.12%
  7. Multiple Allergies (allergy to multiple agents): 2 people, 3.12%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 3.12%
  9. Belching (release of gas from the digestive tract): 2 people, 3.12%
  10. Stress And Anxiety: 2 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec otc and have Nephrosclerosis?

- Check whether Nephrosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prilosec otc:

Nephrosclerosis treatments and more:

How severe was Nephrosclerosis and when was it recovered:

Expand to all the drugs that have ingredients of omeprazole magnesium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prilosec otc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephrosclerosis:

Browse all the conditions that are associated with Nephrosclerosis:


How the study uses the data?

The study uses data from the FDA. It is based on omeprazole magnesium (the active ingredients of Prilosec otc) and Prilosec otc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: