Prilosec and Haemolysis - a phase IV clinical study of FDA data


Haemolysis is found among people who take Prilosec, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Prilosec and have Haemolysis. It is created by eHealthMe based on reports of 165,391 people who have side effects when taking Prilosec from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 01, 2022

165,391 people reported to have side effects when taking Prilosec.
Among them, 64 people (0.04%) have Haemolysis.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 168,968 Prilosec users for its effectiveness, alternative drugs and more.

What is Haemolysis?

Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid) is found to be associated with 1,186 drugs and 784 conditions by eHealthMe.

Number of Prilosec and Haemolysis reports submitted per year:

Could Prilosec cause Haemolysis?

Gender of people who have Haemolysis when taking Prilosec *:

  • female: 66.13 %
  • male: 33.87 %

Age of people who have Haemolysis when taking Prilosec *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 17.54 %
  • 30-39: 14.04 %
  • 40-49: 14.04 %
  • 50-59: 21.05 %
  • 60+: 33.33 %

Common drugs people take besides Prilosec *:

  1. Soliris: 17 people, 26.56%
  2. Folic Acid: 14 people, 21.88%
  3. Prednisone: 10 people, 15.62%
  4. Lasix: 9 people, 14.06%
  5. Coumadin: 8 people, 12.50%
  6. Norvasc: 8 people, 12.50%
  7. Aldactone: 6 people, 9.38%
  8. Ambien: 6 people, 9.38%
  9. Dilaudid: 6 people, 9.38%
  10. Synthroid: 6 people, 9.38%

Common side effects people have besides Haemolysis *:

  1. Anaemia (lack of blood): 16 people, 25.00%
  2. Haemoglobin Decreased: 13 people, 20.31%
  3. Blood Lactate Dehydrogenase Increased: 13 people, 20.31%
  4. Fatigue (feeling of tiredness): 12 people, 18.75%
  5. Thrombocytopenia (decrease of platelets in blood): 12 people, 18.75%
  6. Abdominal Pain: 11 people, 17.19%
  7. Fever: 11 people, 17.19%
  8. Chest Pain: 11 people, 17.19%
  9. Blood Bilirubin Increased: 10 people, 15.62%
  10. Headache (pain in head): 10 people, 15.62%

Common conditions people have *:

  1. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 17 people, 26.56%
  2. Pulmonary Hypertension Primary (increase in blood pressure in the lung artery with no cause): 4 people, 6.25%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 6.25%
  4. Pain: 4 people, 6.25%
  5. Oedema Peripheral (superficial swelling): 4 people, 6.25%
  6. Nausea (feeling of having an urge to vomit): 4 people, 6.25%
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 4.69%
  8. Cellulitis (infection under the skin): 3 people, 4.69%
  9. Fungal Endocarditis (fungal infection of the inner layer of the heart): 3 people, 4.69%
  10. Oesophageal Candidiasis (fungal infection of oesophagus): 3 people, 4.69%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and have Haemolysis?

Check whether Haemolysis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Haemolysis and when was it recovered:

Expand to all the drugs that have ingredients of omeprazole:

Alternative drugs to, pros and cons of Prilosec:

Common Prilosec side effects:

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Haemolysis treatments and more:

COVID vaccines that are related to Haemolysis:

Common drugs associated with Haemolysis:

All the drugs that are associated with Haemolysis:

Common conditions associated with Haemolysis:

All the conditions that are associated with Haemolysis:

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Prilosec) and Prilosec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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