Prilosec and Rectocele - a phase IV clinical study of FDA data

Summary:

Rectocele is reported as a side effect among people who take Prilosec (omeprazole), especially for people who are 60+ old, have been taking the drug for 5 - 10 years also take Fosamax, and have Osteoporosis.

The phase IV clinical study analyzes which people have Rectocele when taking Prilosec. It is created by eHealthMe based on reports of 171,578 people who have side effects when taking Prilosec from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Rectocele?

Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina) is found to be associated with 293 drugs and 319 conditions by eHealthMe. Check the latest studies of Rectocele.

On Jul, 21, 2026

171,578 people reported to have side effects when taking Prilosec.
Among them, 64 people (0.04%) have Rectocele.

Among these 64 people:

How long have people been on Prilosec when they have Rectocele? *

What is the age of people who have Rectocele when taking Prilosec? *

What are other drugs people take besides Prilosec? *

What are other side effects people have besides Rectocele? *

Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth): 42 people, 65.62%
Gallstones (stone formation by bile component): 28 people, 43.75%
Joint Pain: 28 people, 43.75%
Dyspnea (difficult or laboured breathing): 24 people, 37.50%
Acute Kidney Failure: 23 people, 35.94%
Nausea (feeling of having an urge to vomit): 23 people, 35.94%
Femur Fracture: 23 people, 35.94%
Weight Decreased: 23 people, 35.94%
Fatigue (feeling of tiredness): 22 people, 34.38%
High Blood Pressure: 22 people, 34.38%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 26 people, 40.62%
High Blood Pressure: 14 people, 21.88%
Pain: 10 people, 15.62%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 14.06%
Localised Osteoarthritis (infection of joint affects only single joint): 8 people, 12.50%
Gravitational Oedema (abnormally large fluid volume in the circulatory system makes obese): 7 people, 10.94%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 10.94%
Muscle Spasms (muscle contraction): 7 people, 10.94%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 9.38%
Depression: 5 people, 7.81%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and have Rectocele?

- Check whether Rectocele is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prilosec:

Prilosec (175,285 reports)

Rectocele treatments and more:

Rectocele (1,200 reports)

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectocele:

Rectocele (293 drugs)

Browse all the conditions that are associated with Rectocele:

Rectocele (319 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Prilosec) and Prilosec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.