Primaxin and Aplastic anemia - a phase IV clinical study of FDA data
Summary:
Aplastic anemia is reported as a side effect among people who take Primaxin (cilastatin sodium; imipenem), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Analgesia.
The phase IV clinical study analyzes which people have Aplastic anemia when taking Primaxin. It is created by eHealthMe based on reports of 4,534 people who have side effects when taking Primaxin from the FDA, and is updated regularly.
What is Primaxin?
Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.
What is Aplastic anemia?
Aplastic anemia is found to be associated with 623 drugs and 884 conditions by eHealthMe. Check the latest studies of Aplastic anemia.
4,534 people reported to have side effects when taking Primaxin.
Among them, 13 people (0.29%) have Aplastic anemia.

Among these 13 people:
How long have people been on Primaxin when they have Aplastic anemia? *
- < 1 month: 75 %
- 1 - 6 months: 25 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Aplastic anemia when taking Primaxin? *
- female: 53.85 %
- male: 46.15 %
What is the age of people who have Aplastic anemia when taking Primaxin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 23.08 %
- 20-29: 0.0 %
- 30-39: 23.08 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 53.85 %
What are other drugs people take besides Primaxin? *
- Vancomycin: 6 people, 46.15%
- Rocephin: 5 people, 38.46%
- Atenolol: 3 people, 23.08%
- Amlodipine Besylate: 3 people, 23.08%
- Folic Acid: 3 people, 23.08%
- Ramipril: 3 people, 23.08%
- Sevelamer Hydrochloride: 3 people, 23.08%
- Ofloxacin: 3 people, 23.08%
- Sodium Polystyrene Sulfonate: 3 people, 23.08%
- Tamoxifen Citrate: 3 people, 23.08%
What are other side effects people have besides Aplastic anemia? *
- Systemic Inflammatory Response Syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection): 6 people, 46.15%
- Pneumonia: 6 people, 46.15%
- Leukopenia (less number of white blood cells in blood): 5 people, 38.46%
- Pleural Effusion (water on the lungs): 5 people, 38.46%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 38.46%
- Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 5 people, 38.46%
- Acute Kidney Failure: 5 people, 38.46%
- Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 38.46%
- Febrile Neutropenia (fever with reduced white blood cells): 3 people, 23.08%
- Protein Total Abnormal: 2 people, 15.38%
What are the existing conditions these people have? *
- Urinary Tract Infection: 5 people, 38.46%
- Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 38.46%
- Analgesia: 5 people, 38.46%
- Sclerosing Encapsulating Peritonitis (thick peritoneal membranes): 3 people, 23.08%
- High Blood Pressure: 3 people, 23.08%
- Herpes Zoster: 1 person, 7.69%
- Fever: 1 person, 7.69%
- Aspergillosis (an infection caused by a fungus called aspergillus): 1 person, 7.69%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Primaxin and have Aplastic anemia?
- Check whether Aplastic anemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Primaxin:
- Primaxin (4,540 reports)
Aplastic anemia treatments and more:
- Aplastic anemia (14,870 reports)
How severe was Aplastic anemia and when was it recovered:
Expand to all the drugs that have ingredients of cilastatin sodium; imipenem:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Primaxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Aplastic anemia:
- Aplastic anemia (623 drugs)
Browse all the conditions that are associated with Aplastic anemia:
- Aplastic anemia (884 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on cilastatin sodium; imipenem (the active ingredients of Primaxin) and Primaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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