Primaxin and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Primaxin (cilastatin sodium; imipenem), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Prilosec, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Joint pain when taking Primaxin. It is created by eHealthMe based on reports of 4,534 people who have side effects when taking Primaxin from the FDA, and is updated regularly.

What is Primaxin?

Primaxin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 4,540 Primaxin users. Check the latest studies of Primaxin.

What is Joint pain?

Joint pain is found to be associated with 3,331 drugs and 5,207 conditions by eHealthMe. Check the latest studies of Joint pain.



On Jul, 18, 2026

4,534 people reported to have side effects when taking Primaxin.
Among them, 31 people (0.68%) have Joint pain.

Could Primaxin cause Joint pain?

Among these 31 people:

How long have people been on Primaxin when they have Joint pain? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Joint pain when taking Primaxin? *

  • female: 29.03 %
  • male: 70.97 %

What is the age of people who have Joint pain when taking Primaxin? *

  • 0-1: 0.0 %
  • 2-9: 3.57 %
  • 10-19: 3.57 %
  • 20-29: 32.14 %
  • 30-39: 3.57 %
  • 40-49: 39.29 %
  • 50-59: 7.14 %
  • 60+: 10.71 %

What are other drugs people take besides Primaxin? *

  1. Levaquin: 18 people, 58.06%
  2. Prilosec: 18 people, 58.06%
  3. Diflucan: 17 people, 54.84%
  4. Compazine: 16 people, 51.61%
  5. Neurontin: 16 people, 51.61%
  6. Vancomycin: 16 people, 51.61%
  7. Lortab: 15 people, 48.39%
  8. Zometa: 14 people, 45.16%
  9. Aredia: 14 people, 45.16%
  10. Oxycontin: 13 people, 41.94%

What are other side effects people have besides Joint pain? *

  1. Weakness: 20 people, 64.52%
  2. Stress And Anxiety: 20 people, 64.52%
  3. Headache (pain in head): 19 people, 61.29%
  4. Fever: 19 people, 61.29%
  5. Back Pain: 18 people, 58.06%
  6. Pain: 17 people, 54.84%
  7. Oedema Peripheral (superficial swelling): 16 people, 51.61%
  8. High Blood Pressure: 16 people, 51.61%
  9. Neuropathy Peripheral (surface nerve damage): 15 people, 48.39%
  10. Osteoporosis (bones weak and more likely to break): 15 people, 48.39%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 6 people, 19.35%
  2. Pain: 4 people, 12.90%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.68%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.45%
  5. Gynecomastia (enlargement of the gland tissue of the male breast): 2 people, 6.45%
  6. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 6.45%
  7. Depression: 2 people, 6.45%
  8. Febrile Neutropenia (fever with reduced white blood cells): 2 people, 6.45%
  9. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 2 people, 6.45%
  10. Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Primaxin and have Joint pain?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primaxin:

Joint pain treatments and more:

How severe was Joint pain and when was it recovered:

Expand to all the drugs that have ingredients of cilastatin sodium; imipenem:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Primaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Browse all the conditions that are associated with Joint pain:


How the study uses the data?

The study uses data from the FDA. It is based on cilastatin sodium; imipenem (the active ingredients of Primaxin) and Primaxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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