Primidone and Gallstones - a phase IV clinical study of FDA data

Summary:

Gallstones is reported as a side effect among people who take Primidone (primidone), especially for people who are female, 60+ old, also take Folic Acid, and have Restless leg syndrome.

The phase IV clinical study analyzes which people have Gallstones when taking Primidone. It is created by eHealthMe based on reports of 10,125 people who have side effects when taking Primidone from the FDA, and is updated regularly.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

What is Gallstones?

Gallstones (stone formation by bile component) is found to be associated with 1,805 drugs and 2,099 conditions by eHealthMe. Check the latest studies of Gallstones.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

10,125 people reported to have side effects when taking Primidone.
Among them, 48 people (0.47%) have Gallstones.

Among these 48 people:

What is the gender of people who have Gallstones when taking Primidone? *

female: 72.09 %
male: 27.91 %

What is the age of people who have Gallstones when taking Primidone? *

What are other drugs people take besides Primidone? *

What are other side effects people have besides Gallstones? *

Diarrhea: 28 people, 58.33%
Dizziness: 25 people, 52.08%
Weight Decreased: 23 people, 47.92%
Pancreatitis (inflammation of pancreas): 23 people, 47.92%
Restless Leg Syndrome (a powerful urge to move your legs): 21 people, 43.75%
Acute Kidney Failure: 20 people, 41.67%
Arthropathy: 20 people, 41.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 20 people, 41.67%
Neoplasm Malignant (cancer tumour): 19 people, 39.58%
Skin Cancer: 19 people, 39.58%

What are the existing conditions these people have? *

Restless Leg Syndrome (a powerful urge to move your legs): 19 people, 39.58%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 35.42%
High Blood Pressure: 16 people, 33.33%
Blood Iron Decreased: 11 people, 22.92%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 16.67%
Depression: 8 people, 16.67%
Neuropathy Peripheral (surface nerve damage): 7 people, 14.58%
Bipolar Disorder (mood disorder): 7 people, 14.58%
Sleep Disorder: 7 people, 14.58%
High Blood Cholesterol: 7 people, 14.58%

* Approximation only. Some reports may have incomplete information.

Do you take Primidone and have Gallstones?

- Check whether Gallstones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primidone:

Primidone (10,474 reports)

Gallstones treatments and more:

Gallstones (50,126 reports)

Browse all side effects of Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallstones:

Gallstones (1,805 drugs)

Browse all the conditions that are associated with Gallstones:

Gallstones (2,099 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on primidone (the active ingredients of Primidone) and Primidone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.