Primidone and Pseudomembranous colitis - a phase IV clinical study of FDA data

Summary:

Pseudomembranous colitis is reported as a side effect among people who take Primidone (primidone), especially for people who are female, 60+ old, also take Fluconazole, and have Mantle cell lymphoma.

The phase IV clinical study analyzes which people have Pseudomembranous colitis when taking Primidone. It is created by eHealthMe based on reports of 10,125 people who have side effects when taking Primidone from the FDA, and is updated regularly.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

What is Pseudomembranous colitis?

Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon) is found to be associated with 428 drugs and 934 conditions by eHealthMe. Check the latest studies of Pseudomembranous colitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

10,125 people reported to have side effects when taking Primidone.
Among them, 11 people (0.11%) have Pseudomembranous colitis.

Could Primidone cause Pseudomembranous colitis?

Among these 11 people:

What is the gender of people who have Pseudomembranous colitis when taking Primidone? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Pseudomembranous colitis when taking Primidone? *

What are other drugs people take besides Primidone? *

What are other side effects people have besides Pseudomembranous colitis? *

Diarrhea: 9 people, 81.82%
Liver Disorder (liver diseases): 6 people, 54.55%
Hepatitis B: 6 people, 54.55%
Lymphocyte Count Decreased: 5 people, 45.45%
Gastroenteritis (inflammation of stomach and intestine): 5 people, 45.45%
Diarrhea Infectious: 5 people, 45.45%
White Blood Cell Count Decreased: 4 people, 36.36%
Hypokalemia (low potassium): 4 people, 36.36%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 27.27%
Skin Haemorrhage (bleeding into skin): 1 person, 9.09%

What are the existing conditions these people have? *

Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 6 people, 54.55%
Genital Herpes (herpes infection of genital): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Primidone and have Pseudomembranous colitis?

- Check whether Pseudomembranous colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Primidone:

Primidone (10,474 reports)

Browse all side effects of Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pseudomembranous colitis:

Pseudomembranous colitis (428 drugs)

Browse all the conditions that are associated with Pseudomembranous colitis:

Pseudomembranous colitis (934 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on primidone (the active ingredients of Primidone) and Primidone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.