Prinivil and Acidosis - a phase IV clinical study of FDA data

Summary:

Acidosis is reported as a side effect among people who take Prinivil (lisinopril), especially for people who are male, 60+ old, also take Norvasc, and have Bladder transitional cell carcinoma.

The phase IV clinical study analyzes which people have Acidosis when taking Prinivil. It is created by eHealthMe based on reports of 19,973 people who have side effects when taking Prinivil from the FDA, and is updated regularly.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

What is Acidosis?

Acidosis (build-up of carbon dioxide in the blood) is found to be associated with 881 drugs and 1,012 conditions by eHealthMe. Check the latest studies of Acidosis.



On May, 01, 2026

19,973 people reported to have side effects when taking Prinivil.
Among them, 40 people (0.2%) have Acidosis.

Could Prinivil cause Acidosis?

Among these 40 people:

What is the gender of people who have Acidosis when taking Prinivil? *

  • female: 42.5 %
  • male: 57.5 %

What is the age of people who have Acidosis when taking Prinivil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.7 %
  • 30-39: 13.51 %
  • 40-49: 2.7 %
  • 50-59: 29.73 %
  • 60+: 51.35 %

What are other drugs people take besides Prinivil? *

  1. Norvasc: 15 people, 37.50%
  2. Nasonex: 8 people, 20.00%
  3. Prednisone: 7 people, 17.50%
  4. Lopressor: 7 people, 17.50%
  5. Toprol-Xl: 7 people, 17.50%
  6. Celexa: 7 people, 17.50%
  7. Motrin: 6 people, 15.00%
  8. Bactrim Ds: 6 people, 15.00%
  9. Axid: 5 people, 12.50%
  10. Imdur: 5 people, 12.50%

What are other side effects people have besides Acidosis? *

  1. Hypotension (abnormally low blood pressure): 17 people, 42.50%
  2. Hyperkalemia (damage to or disease of the kidney): 16 people, 40.00%
  3. Fatigue (feeling of tiredness): 11 people, 27.50%
  4. Hypovolaemia (a decreased volume of circulating blood in the body): 9 people, 22.50%
  5. Dehydration (dryness resulting from the removal of water): 9 people, 22.50%
  6. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 8 people, 20.00%
  7. Diarrhea: 8 people, 20.00%
  8. Acute Kidney Failure: 7 people, 17.50%
  9. Intussusception: 7 people, 17.50%
  10. Gastrointestinal Necrosis (destruction of gastrointestinal organ): 6 people, 15.00%

What are the existing conditions these people have? *

  1. Bladder Transitional Cell Carcinoma (types of bladder cancer): 6 people, 15.00%
  2. Pain: 2 people, 5.00%
  3. Hiv Infection: 2 people, 5.00%
  4. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 2.50%
  5. Non Small Cell Lung Cancer Stage Iiia (lung cancer stage iiia, meaning a tumour less than 3cm, with no nodes): 1 person, 2.50%
  6. Nausea (feeling of having an urge to vomit): 1 person, 2.50%
  7. Multiple Myeloma (cancer of the plasma cells): 1 person, 2.50%
  8. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 2.50%
  9. Hepatocellular Carcinoma (liver cancer): 1 person, 2.50%
  10. Bladder Cancer: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Prinivil and have Acidosis?

- Check whether Acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prinivil:

Acidosis treatments and more:

How severe was Acidosis and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acidosis:

Browse all the conditions that are associated with Acidosis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Prinivil) and Prinivil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: