Pristiq and Myoclonus - a phase IV clinical study of FDA data

Summary:

Myoclonus is reported as a side effect among people who take Pristiq (desvenlafaxine succinate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Gabapentin, and have Affective disorder.

The phase IV clinical study analyzes which people have Myoclonus when taking Pristiq. It is created by eHealthMe based on reports of 15,699 people who have side effects when taking Pristiq from the FDA, and is updated regularly.

What is Pristiq?

Pristiq has active ingredients of desvenlafaxine succinate. It is often used in depression. eHealthMe is studying from 19,555 Pristiq users. Check the latest studies of Pristiq.

What is Myoclonus?

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles) is found to be associated with 756 drugs and 1,141 conditions by eHealthMe. Check the latest studies of Myoclonus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

15,699 people reported to have side effects when taking Pristiq.
Among them, 11 people (0.07%) have Myoclonus.

Among these 11 people:

How long have people been on Pristiq when they have Myoclonus? *

What is the gender of people who have Myoclonus when taking Pristiq? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Myoclonus when taking Pristiq? *

What are other drugs people take besides Pristiq? *

What are other side effects people have besides Myoclonus? *

Heart Rate Increased: 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Diarrhea: 3 people, 27.27%
Dizziness: 3 people, 27.27%
Headache (pain in head): 3 people, 27.27%
Insomnia (sleeplessness): 3 people, 27.27%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 27.27%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 18.18%
Coordination Abnormal (abnormal movement): 2 people, 18.18%
Disturbance In Attention: 2 people, 18.18%

What are the existing conditions these people have? *

Sleep Disorder: 3 people, 27.27%
Affective Disorder (mental disorder): 3 people, 27.27%
Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 1 person, 9.09%
Post-Traumatic Stress Disorder: 1 person, 9.09%
Pain: 1 person, 9.09%
Neuropathy Peripheral (surface nerve damage): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Hyperthyroidism (over activity of the thyroid gland): 1 person, 9.09%
Headache (pain in head): 1 person, 9.09%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Pristiq and have Myoclonus?

- Check whether Myoclonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pristiq:

Pristiq (19,555 reports)

Myoclonus treatments and more:

Myoclonus (14,211 reports)

Browse all side effects of Pristiq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoclonus:

Myoclonus (756 drugs)

Browse all the conditions that are associated with Myoclonus:

Myoclonus (1,141 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on desvenlafaxine succinate (the active ingredients of Pristiq) and Pristiq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.