Pristiq and Presyncope - a phase IV clinical study of FDA data

Summary:

Presyncope is reported as a side effect among people who take Pristiq (desvenlafaxine succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xanax, and have Enlarged prostate.

The phase IV clinical study analyzes which people have Presyncope when taking Pristiq. It is created by eHealthMe based on reports of 15,699 people who have side effects when taking Pristiq from the FDA, and is updated regularly.

What is Pristiq?

Pristiq has active ingredients of desvenlafaxine succinate. It is often used in depression. eHealthMe is studying from 19,555 Pristiq users. Check the latest studies of Pristiq.

What is Presyncope?

Presyncope is found to be associated with 1,357 drugs and 1,286 conditions by eHealthMe. Check the latest studies of Presyncope.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

15,699 people reported to have side effects when taking Pristiq.
Among them, 35 people (0.22%) have Presyncope.

Among these 35 people:

How long have people been on Pristiq when they have Presyncope? *

What is the gender of people who have Presyncope when taking Pristiq? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Presyncope when taking Pristiq? *

What are other drugs people take besides Pristiq? *

Xanax: 5 people, 14.29%
Alfuzosin Hydrochloride: 3 people, 8.57%
Truvada: 3 people, 8.57%
Centrum Silver: 3 people, 8.57%
Testim: 3 people, 8.57%
Kaletra: 3 people, 8.57%
Abilify: 2 people, 5.71%
Simvastatin: 2 people, 5.71%
Prevacid: 2 people, 5.71%
Lisinopril: 2 people, 5.71%

What are other side effects people have besides Presyncope? *

Dizziness: 16 people, 45.71%
Nausea (feeling of having an urge to vomit): 11 people, 31.43%
Headache (pain in head): 7 people, 20.00%
Loss Of Consciousness: 6 people, 17.14%
Hyperhidrosis (abnormally increased sweating): 6 people, 17.14%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 5 people, 14.29%
Feeling Abnormal: 5 people, 14.29%
Constipation: 4 people, 11.43%
Weakness: 4 people, 11.43%
Fatigue (feeling of tiredness): 4 people, 11.43%

What are the existing conditions these people have? *

Hiv Test Positive: 3 people, 8.57%
High Blood Pressure: 3 people, 8.57%
Enlarged Prostate: 3 people, 8.57%
Gastric Disorder (disease of stomach): 2 people, 5.71%
Quit Smoking: 2 people, 5.71%
Diabetes: 2 people, 5.71%
Weight Decreased: 1 person, 2.86%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 2.86%
Chronic Myeloid Leukaemia (In Remission): 1 person, 2.86%
Delusion (a false belief or opinion): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Pristiq and have Presyncope?

- Check whether Presyncope is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pristiq:

Pristiq (19,555 reports)

Presyncope treatments and more:

Presyncope (26,156 reports)

Browse all side effects of Pristiq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Presyncope:

Presyncope (1,357 drugs)

Browse all the conditions that are associated with Presyncope:

Presyncope (1,286 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on desvenlafaxine succinate (the active ingredients of Pristiq) and Pristiq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.