Proamatine and Scoliosis - a phase IV clinical study of FDA data

Summary:

Scoliosis is reported as a side effect among people who take Proamatine (midodrine hydrochloride), especially for people who are female, 50-59 old, also take Digoxin, and have Hypercalcaemia of malignancy.

The phase IV clinical study analyzes which people have Scoliosis when taking Proamatine. It is created by eHealthMe based on reports of 946 people who have side effects when taking Proamatine from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Scoliosis?

Scoliosis (a medical condition in which a person's spine is curved from side to side) is found to be associated with 1,033 drugs and 1,099 conditions by eHealthMe. Check the latest studies of Scoliosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

946 people reported to have side effects when taking Proamatine.
Among them, 21 people (2.22%) have Scoliosis.

Among these 21 people:

What is the gender of people who have Scoliosis when taking Proamatine? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Scoliosis when taking Proamatine? *

What are other drugs people take besides Proamatine? *

What are other side effects people have besides Scoliosis? *

Jaw Fracture: 20 people, 95.24%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 20 people, 95.24%
Weight Decreased: 20 people, 95.24%
Impaired Healing: 20 people, 95.24%
Osteomyelitis (infection of bone): 20 people, 95.24%
Osteonecrosis Of Jaw (death of bone of jaw): 20 people, 95.24%
Osteopenia (a condition where bone mineral density is lower than normal): 20 people, 95.24%
Pain: 20 people, 95.24%
Hearing Loss: 20 people, 95.24%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 20 people, 95.24%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 17 people, 80.95%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 17 people, 80.95%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 12 people, 57.14%
Toothaches (tooth pain): 3 people, 14.29%
Muscle Spasms (muscle contraction): 3 people, 14.29%
Depression: 3 people, 14.29%
Bone Neoplasm Malignant (cancer of bone): 2 people, 9.52%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 4.76%
High Blood Pressure: 1 person, 4.76%
High Blood Cholesterol: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Proamatine and have Scoliosis?

- Check whether Scoliosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Proamatine:

Proamatine (968 reports)

Scoliosis treatments and more:

Scoliosis (11,685 reports)

Browse all side effects of Proamatine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Scoliosis:

Scoliosis (1,033 drugs)

Browse all the conditions that are associated with Scoliosis:

Scoliosis (1,099 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Proamatine) and Proamatine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.