Proamatine and Spinal column stenosis - a phase IV clinical study of FDA data

Summary:

Spinal column stenosis is reported as a side effect among people who take Proamatine (midodrine hydrochloride), especially for people who are male, 60+ old, also take Spironolactone, and have Muscle spasms.

The phase IV clinical study analyzes which people have Spinal column stenosis when taking Proamatine. It is created by eHealthMe based on reports of 946 people who have side effects when taking Proamatine from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Spinal column stenosis?

Spinal column stenosis (narrowing of spinal column) is found to be associated with 841 drugs and 739 conditions by eHealthMe. Check the latest studies of Spinal column stenosis.

On Jul, 10, 2026

946 people reported to have side effects when taking Proamatine.
Among them, 11 people (1.16%) have Spinal column stenosis.

Could Proamatine cause Spinal column stenosis?

Among these 11 people:

What is the gender of people who have Spinal column stenosis when taking Proamatine? *

female: 9.09 %
male: 90.91 %

What is the age of people who have Spinal column stenosis when taking Proamatine? *

What are other drugs people take besides Proamatine? *

What are other side effects people have besides Spinal column stenosis? *

Weight Decreased: 11 people, 100.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 100.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 11 people, 100.00%
Dysaesthesia (abnormal sensation): 11 people, 100.00%
Dyspnea (difficult or laboured breathing): 11 people, 100.00%
Ejection Fraction Decreased (systolic heart failure): 11 people, 100.00%
Enlarged Heart: 11 people, 100.00%
Fainting (loss of consciousness and postural tone): 11 people, 100.00%
Fall: 11 people, 100.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 100.00%

What are the existing conditions these people have? *

Toothaches (tooth pain): 11 people, 100.00%
Muscle Spasms (muscle contraction): 11 people, 100.00%
Depression: 4 people, 36.36%
Bone Neoplasm Malignant (cancer of bone): 3 people, 27.27%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 9.09%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Proamatine and have Spinal column stenosis?

- Check whether Spinal column stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Proamatine:

Proamatine (968 reports)

Browse all side effects of Proamatine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal column stenosis:

Spinal column stenosis (841 drugs)

Browse all the conditions that are associated with Spinal column stenosis:

Spinal column stenosis (739 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Proamatine) and Proamatine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.