Probiotic and Lyme disease - a phase IV clinical study of FDA data

Summary:

Lyme disease is reported as a side effect among people who take Probiotic (bacillus coagulans), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fish Oil, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Lyme disease when taking Probiotic. It is created by eHealthMe based on reports of 21,552 people who have side effects when taking Probiotic from the FDA, and is updated regularly.

What is Probiotic?

Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,461 Probiotic users. Check the latest studies of Probiotic.

What is Lyme disease?

Lyme disease (a bacterial infection that is spread to humans by infected ticks) is found to be associated with 430 drugs and 620 conditions by eHealthMe. Check the latest studies of Lyme disease.



On Jul, 30, 2026

21,552 people reported to have side effects when taking Probiotic.
Among them, 26 people (0.12%) have Lyme disease.

Could Probiotic cause Lyme disease?

Among these 26 people:

How long have people been on Probiotic when they have Lyme disease? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lyme disease when taking Probiotic? *

  • female: 80.77 %
  • male: 19.23 %

What is the age of people who have Lyme disease when taking Probiotic? *

  • 0-1: 0.0 %
  • 2-9: 13.33 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.67 %
  • 40-49: 20.0 %
  • 50-59: 20.0 %
  • 60+: 40.0 %

What are other drugs people take besides Probiotic? *

  1. Fish Oil: 10 people, 38.46%
  2. Vitamin D3: 9 people, 34.62%
  3. Coenzyme Q10: 8 people, 30.77%
  4. Vitamin C: 6 people, 23.08%
  5. Xyrem: 5 people, 19.23%
  6. Synthroid: 5 people, 19.23%
  7. Cymbalta: 5 people, 19.23%
  8. Magnesium: 4 people, 15.38%
  9. Vitamin B12: 4 people, 15.38%
  10. Naltrexone: 4 people, 15.38%

What are other side effects people have besides Lyme disease? *

  1. Fatigue (feeling of tiredness): 7 people, 26.92%
  2. Rashes (redness): 4 people, 15.38%
  3. Weight Decreased: 3 people, 11.54%
  4. Fall: 3 people, 11.54%
  5. Weakness: 3 people, 11.54%
  6. Malaise (a feeling of general discomfort or uneasiness): 3 people, 11.54%
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 11.54%
  8. Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 2 people, 7.69%
  9. Fungal Test Positive: 2 people, 7.69%
  10. High Blood Cholesterol: 2 people, 7.69%

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 6 people, 23.08%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 19.23%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 15.38%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 11.54%
  6. High Blood Pressure: 3 people, 11.54%
  7. Pain: 3 people, 11.54%
  8. Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 7.69%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.69%
  10. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Probiotic and have Lyme disease?

- Check whether Lyme disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Probiotic:

Lyme disease treatments and more:

How severe was Lyme disease and when was it recovered:

Expand to all the drugs that have ingredients of bacillus coagulans:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Probiotic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lyme disease:

Browse all the conditions that are associated with Lyme disease:


How the study uses the data?

The study uses data from the FDA. It is based on bacillus coagulans (the active ingredients of Probiotic) and Probiotic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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