Probiotic and Rectal prolapse - a phase IV clinical study of FDA data

Summary:

Rectal prolapse is reported as a side effect among people who take Probiotic (bacillus coagulans), especially for people who are female, 60+ old, also take Calcium, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Rectal prolapse when taking Probiotic. It is created by eHealthMe based on reports of 21,552 people who have side effects when taking Probiotic from the FDA, and is updated regularly.

What is Probiotic?

Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,462 Probiotic users. Check the latest studies of Probiotic.

What is Rectal prolapse?

Rectal prolapse (falling of rectum from normal place) is found to be associated with 307 drugs and 341 conditions by eHealthMe. Check the latest studies of Rectal prolapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

21,552 people reported to have side effects when taking Probiotic.
Among them, 11 people (0.05%) have Rectal prolapse.

Among these 11 people:

What is the gender of people who have Rectal prolapse when taking Probiotic? *

female: 100 %
male: 0.0 %

What is the age of people who have Rectal prolapse when taking Probiotic? *

What are other drugs people take besides Probiotic? *

Vitamin D3: 6 people, 54.55%
Calcium: 6 people, 54.55%
Miralax: 5 people, 45.45%
Jakafi: 5 people, 45.45%
Symbicort: 5 people, 45.45%
Promethazine Hydrochloride: 3 people, 27.27%
Benzonatate: 3 people, 27.27%
Nitroglycerin: 3 people, 27.27%
Montelukast Sodium: 3 people, 27.27%
Sucralfate: 3 people, 27.27%

What are other side effects people have besides Rectal prolapse? *

Haemoglobin Decreased: 6 people, 54.55%
Anorectal Disorder: 5 people, 45.45%
Breast Cancer: 5 people, 45.45%
Weakness: 3 people, 27.27%
Pain: 3 people, 27.27%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 18.18%
Muscle Spasms (muscle contraction): 2 people, 18.18%
Fatigue (feeling of tiredness): 2 people, 18.18%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 18.18%
Hair Loss: 2 people, 18.18%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 5 people, 45.45%
Asthma: 3 people, 27.27%
Depression: 3 people, 27.27%
Type 2 Diabetes: 2 people, 18.18%
Dry Eyes (lack of adequate tears): 2 people, 18.18%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 18.18%
Gastric Infection (infection of stomach): 2 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 18.18%
Hypersensitivity: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Probiotic and have Rectal prolapse?

- Check whether Rectal prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Probiotic:

Probiotic (22,462 reports)

Rectal prolapse treatments and more:

Rectal prolapse (1,711 reports)

Browse all side effects of Probiotic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal prolapse:

Rectal prolapse (307 drugs)

Browse all the conditions that are associated with Rectal prolapse:

Rectal prolapse (341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bacillus coagulans (the active ingredients of Probiotic) and Probiotic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.