Proctofoam hc and Fatigue aggravated - a phase IV clinical study of FDA data

Summary:

Fatigue aggravated is reported as a side effect among people who take Proctofoam hc (hydrocortisone acetate; pramoxine hydrochloride), especially for people who are male, 60+ old, also take Triamcinolone, and have Pain.

The phase IV clinical study analyzes which people have Fatigue aggravated when taking Proctofoam hc. It is created by eHealthMe based on reports of 548 people who have side effects when taking Proctofoam hc from the FDA, and is updated regularly.

What is Proctofoam hc?

Proctofoam hc has active ingredients of hydrocortisone acetate; pramoxine hydrochloride. It is often used in hemorrhoids. eHealthMe is studying from 555 Proctofoam hc users. Check the latest studies of Proctofoam hc.

What is Fatigue aggravated?

Fatigue aggravated (feeling of tiredness) is found to be associated with 3,163 drugs and 1,117 conditions by eHealthMe. Check the latest studies of Fatigue aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

548 people reported to have side effects when taking Proctofoam hc.
Among them, 16 people (2.92%) have Fatigue aggravated.

Could Proctofoam hc cause Fatigue aggravated?

Among these 16 people:

What is the gender of people who have Fatigue aggravated when taking Proctofoam hc? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Fatigue aggravated when taking Proctofoam hc? *

What are other drugs people take besides Proctofoam hc? *

What are other side effects people have besides Fatigue aggravated? *

Weakness: 7 people, 43.75%
Nausea (feeling of having an urge to vomit): 6 people, 37.50%
Diarrhea: 6 people, 37.50%
Weight Decreased: 5 people, 31.25%
Rectal Haemorrhage (bleeding from anus): 5 people, 31.25%
Defaecation Urgency (a sudden compelling urge to defecate): 5 people, 31.25%
Blood Creatine Phosphokinase Increased: 4 people, 25.00%
Muscle Aches (muscle pain): 4 people, 25.00%
Liver Function Test Abnormal: 4 people, 25.00%
Dyspnea (difficult or laboured breathing): 4 people, 25.00%

What are the existing conditions these people have? *

Pain: 4 people, 25.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 18.75%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 12.50%
Stress And Anxiety: 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
Nausea And Vomiting: 2 people, 12.50%
Depression: 2 people, 12.50%
Constipation: 1 person, 6.25%
Birth Control: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Proctofoam hc and have Fatigue aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Proctofoam hc:

Proctofoam hc (555 reports)

Fatigue aggravated treatments and more:

Fatigue aggravated (252 reports)

How severe was Fatigue aggravated and when was it recovered:

Fatigue aggravated in Proctofoam hc

Expand to all the drugs that have ingredients of hydrocortisone acetate; pramoxine hydrochloride:

Fatigue aggravated and drugs with ingredients of hydrocortisone acetate; pramoxine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Proctofoam hc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue aggravated:

Fatigue aggravated (3,164 drugs)

Browse all the conditions that are associated with Fatigue aggravated:

Fatigue aggravated (1,117 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone acetate; pramoxine hydrochloride (the active ingredients of Proctofoam hc) and Proctofoam hc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.