Progesterone and Blister - a phase IV clinical study of FDA data

Summary:

Blister is reported as a side effect among people who take Progesterone (progesterone), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Estradiol, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Blister when taking Progesterone. It is created by eHealthMe based on reports of 20,008 people who have side effects when taking Progesterone from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,022 Progesterone users. Check the latest studies of Progesterone.

What is Blister?

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure) is found to be associated with 1,872 drugs and 2,177 conditions by eHealthMe. Check the latest studies of Blister.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

20,008 people reported to have side effects when taking Progesterone.
Among them, 41 people (0.2%) have Blister.

Could Progesterone cause Blister?

Among these 41 people:

How long have people been on Progesterone when they have Blister? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Blister when taking Progesterone? *

  • female: 97.44 %
  • male: 2.56 %

What is the age of people who have Blister when taking Progesterone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.23 %
  • 30-39: 9.68 %
  • 40-49: 16.13 %
  • 50-59: 41.94 %
  • 60+: 29.03 %

What are other drugs people take besides Progesterone? *

  1. Estradiol: 11 people, 26.83%
  2. Vitamin C: 10 people, 24.39%
  3. Vitamin D3: 8 people, 19.51%
  4. Dexilant: 7 people, 17.07%
  5. Zantac: 7 people, 17.07%
  6. Symbicort: 6 people, 14.63%
  7. Meclizine: 6 people, 14.63%
  8. Synthroid: 6 people, 14.63%
  9. Forteo: 6 people, 14.63%
  10. Cymbalta: 6 people, 14.63%

What are other side effects people have besides Blister? *

  1. Pain: 9 people, 21.95%
  2. Rashes (redness): 9 people, 21.95%
  3. Scar: 8 people, 19.51%
  4. Nasopharyngitis (inflammation of the nasopharynx): 7 people, 17.07%
  5. Fatigue (feeling of tiredness): 7 people, 17.07%
  6. Bone Density Abnormal: 6 people, 14.63%
  7. Infusion Site Pruritus (severe itching at infusion site): 6 people, 14.63%
  8. Weakness: 6 people, 14.63%
  9. Infusion Site Abscess: 6 people, 14.63%
  10. Itching Scar: 6 people, 14.63%

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 6 people, 14.63%
  2. Immunodeficiency: 5 people, 12.20%
  3. Eye Inflammation: 4 people, 9.76%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.88%
  5. Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 2.44%
  6. Insulin Resistance: 1 person, 2.44%
  7. Actinic Keratosis (skin disease due to sun exposure): 1 person, 2.44%
  8. Blood Pressure Abnormal: 1 person, 2.44%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 2.44%
  10. Depression: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Progesterone and have Blister?

- Check whether Blister is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Progesterone:

Blister treatments and more:

How severe was Blister and when was it recovered:

Expand to all the drugs that have ingredients of progesterone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Progesterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blister:

Browse all the conditions that are associated with Blister:


How the study uses the data?

The study uses data from the FDA. It is based on progesterone (the active ingredients of Progesterone) and Progesterone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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