Progesterone and Lyme disease - a phase IV clinical study of FDA data

Summary:

Lyme disease is reported as a side effect among people who take Progesterone (progesterone), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Biotin, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Lyme disease when taking Progesterone. It is created by eHealthMe based on reports of 20,008 people who have side effects when taking Progesterone from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

What is Lyme disease?

Lyme disease (a bacterial infection that is spread to humans by infected ticks) is found to be associated with 433 drugs and 619 conditions by eHealthMe. Check the latest studies of Lyme disease.

On Apr, 28, 2026

20,008 people reported to have side effects when taking Progesterone.
Among them, 26 people (0.13%) have Lyme disease.

Among these 26 people:

How long have people been on Progesterone when they have Lyme disease? *

What is the gender of people who have Lyme disease when taking Progesterone? *

female: 96.15 %
male: 3.85 %

What is the age of people who have Lyme disease when taking Progesterone? *

What are other drugs people take besides Progesterone? *

What are other side effects people have besides Lyme disease? *

Fatigue (feeling of tiredness): 7 people, 26.92%
Oral Herpes (viral infection of mouth): 6 people, 23.08%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 23.08%
Dehydration (dryness resulting from the removal of water): 6 people, 23.08%
Fibrin D Dimer Increased: 6 people, 23.08%
Haematocrit Increased: 6 people, 23.08%
Hormone Level Abnormal: 6 people, 23.08%
Joint Pain: 6 people, 23.08%
Electrocardiogram Abnormal: 5 people, 19.23%
Hair Loss: 5 people, 19.23%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 10 people, 38.46%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 15.38%
Sleep Disorder: 4 people, 15.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 11.54%
Tinnitus (a ringing in the ears): 2 people, 7.69%
High Blood Pressure: 2 people, 7.69%
Hot Flush (sudden feelings of heat): 2 people, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.69%
Insomnia (sleeplessness): 1 person, 3.85%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Progesterone and have Lyme disease?

- Check whether Lyme disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Progesterone:

Progesterone (21,021 reports)

Lyme disease treatments and more:

Lyme disease (6,357 reports)

Browse all side effects of Progesterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lyme disease:

Lyme disease (433 drugs)

Browse all the conditions that are associated with Lyme disease:

Lyme disease (619 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on progesterone (the active ingredients of Progesterone) and Progesterone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.