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Progesterone and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Progesterone (progesterone), especially for people who are female, 40-49 old, also take Aubagio, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Progesterone. It is created by eHealthMe based on reports of 20,008 people who have side effects when taking Progesterone from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,085 drugs and 1,365 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

20,008 people reported to have side effects when taking Progesterone.
Among them, 68 people (0.34%) have Multiple sclerosis.

Could Progesterone cause Multiple sclerosis?

Among these 68 people:

What is the gender of people who have Multiple sclerosis when taking Progesterone? *

  • female: 98.53 %
  • male: 1.47 %

What is the age of people who have Multiple sclerosis when taking Progesterone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.08 %
  • 40-49: 50.0 %
  • 50-59: 27.08 %
  • 60+: 20.83 %

What are other drugs people take besides Progesterone? *

  1. Aubagio: 16 people, 23.53%
  2. Estrace: 15 people, 22.06%
  3. Actemra: 14 people, 20.59%
  4. Celebrex: 14 people, 20.59%
  5. Copaxone: 14 people, 20.59%
  6. Vitamin D3: 12 people, 17.65%
  7. Ampyra: 11 people, 16.18%
  8. Methotrexate: 9 people, 13.24%
  9. Baclofen: 8 people, 11.76%
  10. Tamsulosin: 7 people, 10.29%

What are other side effects people have besides Multiple sclerosis? *

  1. Diarrhea: 22 people, 32.35%
  2. Hypoaesthesia (reduced sense of touch or sensation): 18 people, 26.47%
  3. Urinary Tract Infection: 18 people, 26.47%
  4. Influenza Like Illness: 18 people, 26.47%
  5. Rashes (redness): 18 people, 26.47%
  6. Sinusitis (inflammation of sinus): 18 people, 26.47%
  7. Fever: 18 people, 26.47%
  8. Joint Pain: 18 people, 26.47%
  9. Fatigue (feeling of tiredness): 17 people, 25.00%
  10. Abdominal Pain: 17 people, 25.00%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 22.06%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 8.82%
  3. Muscle Spasms (muscle contraction): 5 people, 7.35%
  4. Pain: 4 people, 5.88%
  5. Stress And Anxiety: 4 people, 5.88%
  6. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 5.88%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 5.88%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 5.88%
  9. Gait Disturbance: 4 people, 5.88%
  10. Depression: 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Progesterone and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Progesterone:

Multiple sclerosis treatments and more:

How severe was Multiple sclerosis and when was it recovered:

Expand to all the drugs that have ingredients of progesterone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Progesterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Browse all the conditions that are associated with Multiple sclerosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on progesterone (the active ingredients of Progesterone) and Progesterone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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