Progesterone and Skin atrophy - a phase IV clinical study of FDA data

Summary:

Skin atrophy is reported as a side effect among people who take Progesterone (progesterone), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Estradiol, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Skin atrophy when taking Progesterone. It is created by eHealthMe based on reports of 20,008 people who have side effects when taking Progesterone from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

What is Skin atrophy?

Skin atrophy (wasting of skin) is found to be associated with 623 drugs and 718 conditions by eHealthMe. Check the latest studies of Skin atrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

20,008 people reported to have side effects when taking Progesterone.
Among them, 13 people (0.06%) have Skin atrophy.

Among these 13 people:

How long have people been on Progesterone when they have Skin atrophy? *

What is the gender of people who have Skin atrophy when taking Progesterone? *

female: 100 %
male: 0.0 %

What is the age of people who have Skin atrophy when taking Progesterone? *

What are other drugs people take besides Progesterone? *

What are other side effects people have besides Skin atrophy? *

Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone): 4 people, 30.77%
Drug Ineffective: 4 people, 30.77%
Weakness: 3 people, 23.08%
Eye Disorder: 3 people, 23.08%
Memory Loss: 3 people, 23.08%
Dyspnea (difficult or laboured breathing): 3 people, 23.08%
Cataract (clouding of the lens inside the eye): 3 people, 23.08%
Alopecia Areata (patchy baldness that typically begins with rapid hair loss): 2 people, 15.38%
Diplopia (double vision): 2 people, 15.38%
Joint Pain: 2 people, 15.38%

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 23.08%
Migraine (headache): 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Dry Eyes (lack of adequate tears): 1 person, 7.69%
Back Pain: 1 person, 7.69%
Bipolar Disorder (mood disorder): 1 person, 7.69%
Colitis Microscopic (inflammation of colon with diarrhoea and abdominal cramps): 1 person, 7.69%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.69%
Diabetes: 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Progesterone and have Skin atrophy?

- Check whether Skin atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Progesterone:

Progesterone (21,021 reports)

Skin atrophy treatments and more:

Skin atrophy (6,670 reports)

Browse all side effects of Progesterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin atrophy:

Skin atrophy (623 drugs)

Browse all the conditions that are associated with Skin atrophy:

Skin atrophy (718 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on progesterone (the active ingredients of Progesterone) and Progesterone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.