Prograf and Epilepsy - a phase IV clinical study of FDA data

Summary:

Epilepsy is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cellcept, and have High blood pressure.

The phase IV clinical study analyzes which people have Epilepsy when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Epilepsy?

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures) is found to be associated with 1,163 drugs and 1,776 conditions by eHealthMe. Check the latest studies of Epilepsy.

On Jul, 08, 2026

41,725 people reported to have side effects when taking Prograf.
Among them, 94 people (0.23%) have Epilepsy.

Among these 94 people:

How long have people been on Prograf when they have Epilepsy? *

What is the gender of people who have Epilepsy when taking Prograf? *

female: 54.35 %
male: 45.65 %

What is the age of people who have Epilepsy when taking Prograf? *

What are other drugs people take besides Prograf? *

What are other side effects people have besides Epilepsy? *

Urinary Tract Infection: 12 people, 12.77%
Infection: 12 people, 12.77%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 11 people, 11.70%
Fever: 10 people, 10.64%
Aspartate Aminotransferase Increased: 10 people, 10.64%
Hepatic Function Abnormal: 10 people, 10.64%
Alanine Aminotransferase Increased: 10 people, 10.64%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 10.64%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 9 people, 9.57%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 9 people, 9.57%

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 12.77%
Gastric Ulcer (stomach ulcer): 11 people, 11.70%
Immunodeficiency Disorders: 7 people, 7.45%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 7.45%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 7 people, 7.45%
Muscle Spasms (muscle contraction): 7 people, 7.45%
Asthma: 7 people, 7.45%
Diarrhea: 6 people, 6.38%
Liver Disorder (liver diseases): 6 people, 6.38%
Dry Eyes (lack of adequate tears): 5 people, 5.32%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and have Epilepsy?

- Check whether Epilepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prograf:

Prograf (42,230 reports)

Epilepsy treatments and more:

Epilepsy (129,285 reports)

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epilepsy:

Epilepsy (1,163 drugs)

Browse all the conditions that are associated with Epilepsy:

Epilepsy (1,776 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.