Prograf and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are male, 30-39 old, have been taking the drug for 6 - 12 months also take Amlodipine, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,008 drugs and 1,435 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Feb, 21, 2026

41,725 people reported to have side effects when taking Prograf.
Among them, 43 people (0.1%) have Hyperthyroidism.

Among these 43 people:

How long have people been on Prograf when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Prograf? *

female: 31.71 %
male: 68.29 %

What is the age of people who have Hyperthyroidism when taking Prograf? *

What are other drugs people take besides Prograf? *

Amlodipine: 19 people, 44.19%
Prednisone: 16 people, 37.21%
Methylprednisolone: 12 people, 27.91%
Tacrolimus: 12 people, 27.91%
Ramipril: 12 people, 27.91%
Lamivudine: 12 people, 27.91%
Mycophenolate Mofetil: 12 people, 27.91%
Bactrim: 11 people, 25.58%
Cellcept: 10 people, 23.26%
Doxazosin Mesylate: 9 people, 20.93%

What are other side effects people have besides Hyperthyroidism? *

Anaemia (lack of blood): 21 people, 48.84%
High Blood Cholesterol: 20 people, 46.51%
Visual Field Defect: 20 people, 46.51%
Hypertriglyceridaemia (excess of triglycerides in the blood): 20 people, 46.51%
Optic Nerve Disorder (disease of optic nerve): 20 people, 46.51%
Toxic Neuropathy (nerve damage caused by toxic (harmful) substances): 20 people, 46.51%
Optic Atrophy (the loss of a proportion of optic disc nerve fibres): 20 people, 46.51%
Toxic Optic Neuropathy (optic nerve damage caused by toxic (harmful) substances): 19 people, 44.19%
Complications Of Transplanted Kidney: 18 people, 41.86%
Diabetes: 6 people, 13.95%

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 48.84%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 20 people, 46.51%
Hyperlipidaemia (presence of excess lipids in the blood): 20 people, 46.51%
Hepatitis B: 20 people, 46.51%
Immunodeficiency Disorders: 6 people, 13.95%
Pain: 1 person, 2.33%
Multiple Fractures: 1 person, 2.33%
Liver Transplant Rejection (failure of liver transplant): 1 person, 2.33%
Hypersensitivity: 1 person, 2.33%
Gout (uric acid crystals building up in the body): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prograf:

Prograf (42,230 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,831 reports)

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,008 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,435 conditions)

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.