Prograf and Increased tendency to bruise - a phase IV clinical study of FDA data

Summary:

Increased tendency to bruise is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are male, 60+ old, also take Jakafi, and have Graft versus host disease.

The phase IV clinical study analyzes which people have Increased tendency to bruise when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Increased tendency to bruise?

Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone) is found to be associated with 768 drugs and 813 conditions by eHealthMe. Check the latest studies of Increased tendency to bruise.



On Jul, 31, 2026

41,725 people reported to have side effects when taking Prograf.
Among them, 12 people (0.03%) have Increased tendency to bruise.

Could Prograf cause Increased tendency to bruise?

Among these 12 people:

What is the gender of people who have Increased tendency to bruise when taking Prograf? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Increased tendency to bruise when taking Prograf? *

  • 0-1: 0.0 %
  • 2-9: 20 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 80 %

What are other drugs people take besides Prograf? *

  1. Jakafi: 5 people, 41.67%
  2. Zovirax: 4 people, 33.33%
  3. Advair Hfa: 4 people, 33.33%
  4. Flovent: 4 people, 33.33%
  5. Sodium Bicarbonate: 3 people, 25.00%
  6. Bortezomib: 3 people, 25.00%
  7. Cyclophosphamide: 3 people, 25.00%
  8. Deltasone: 3 people, 25.00%
  9. Dexamethasone: 3 people, 25.00%
  10. Fluconazole: 3 people, 25.00%

What are other side effects people have besides Increased tendency to bruise? *

  1. Weakness: 7 people, 58.33%
  2. Nausea (feeling of having an urge to vomit): 6 people, 50.00%
  3. Dyspnea Exertional: 6 people, 50.00%
  4. Headache (pain in head): 5 people, 41.67%
  5. Diarrhea: 5 people, 41.67%
  6. Haemorrhage (bleeding): 4 people, 33.33%
  7. Disease Progression: 4 people, 33.33%
  8. Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 4 people, 33.33%
  9. Graft Versus Host Disease In Lung (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the lung): 4 people, 33.33%
  10. Skin Haemorrhage (bleeding into skin): 4 people, 33.33%

What are the existing conditions these people have? *

  1. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 5 people, 41.67%
  2. Pain: 3 people, 25.00%
  3. Nausea (feeling of having an urge to vomit): 3 people, 25.00%
  4. Multiple Myeloma (cancer of the plasma cells): 3 people, 25.00%
  5. Irritability: 3 people, 25.00%
  6. Erection Problems: 3 people, 25.00%
  7. Diarrhea: 3 people, 25.00%
  8. Platelet Count Abnormal: 2 people, 16.67%
  9. Nephropathy (damage to or disease of a kidney): 1 person, 8.33%
  10. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and have Increased tendency to bruise?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prograf:

Increased tendency to bruise treatments and more:

How severe was Increased tendency to bruise and when was it recovered:

Expand to all the drugs that have ingredients of tacrolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Increased tendency to bruise:

Browse all the conditions that are associated with Increased tendency to bruise:


How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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