Prograf and Procedural pain - a phase IV clinical study of FDA data

Summary:

Procedural pain is reported as a side effect among people who take Prograf (tacrolimus), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Miralax, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Procedural pain when taking Prograf. It is created by eHealthMe based on reports of 41,725 people who have side effects when taking Prograf from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Procedural pain?

Procedural pain is found to be associated with 994 drugs and 926 conditions by eHealthMe. Check the latest studies of Procedural pain.



On Jul, 25, 2026

41,725 people reported to have side effects when taking Prograf.
Among them, 21 people (0.05%) have Procedural pain.

Could Prograf cause Procedural pain?

Among these 21 people:

How long have people been on Prograf when they have Procedural pain? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 75 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Procedural pain when taking Prograf? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Procedural pain when taking Prograf? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 12.5 %
  • 20-29: 31.25 %
  • 30-39: 50.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 6.25 %

What are other drugs people take besides Prograf? *

  1. Miralax: 6 people, 28.57%
  2. Valcyte: 5 people, 23.81%
  3. Sulfamethoxazole And Trimethoprim: 4 people, 19.05%
  4. Morphine: 4 people, 19.05%
  5. Lipitor: 4 people, 19.05%
  6. Fluoxetine: 4 people, 19.05%
  7. Zofran: 4 people, 19.05%
  8. Colace: 4 people, 19.05%
  9. Ubiquinone: 4 people, 19.05%
  10. Myfortic: 3 people, 14.29%

What are other side effects people have besides Procedural pain? *

  1. Itching: 6 people, 28.57%
  2. Abdominal Pain: 4 people, 19.05%
  3. High Blood Pressure: 4 people, 19.05%
  4. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 4 people, 19.05%
  5. Heart Rate Increased: 4 people, 19.05%
  6. Urinary Tract Infection: 4 people, 19.05%
  7. Altered State Of Consciousness (altered state of mind): 4 people, 19.05%
  8. Dyspnea (difficult or laboured breathing): 3 people, 14.29%
  9. Pain: 3 people, 14.29%
  10. Coma Hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma): 2 people, 9.52%

What are the existing conditions these people have? *

  1. Pain: 5 people, 23.81%
  2. Immunodeficiency Disorders: 5 people, 23.81%
  3. Anaesthesia: 4 people, 19.05%
  4. Nausea And Vomiting: 2 people, 9.52%
  5. Nausea (feeling of having an urge to vomit): 2 people, 9.52%
  6. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.76%
  7. Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 4.76%
  8. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 4.76%
  9. High Blood Pressure: 1 person, 4.76%
  10. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and have Procedural pain?

- Check whether Procedural pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prograf:

Procedural pain treatments and more:

How severe was Procedural pain and when was it recovered:

Expand to all the drugs that have ingredients of tacrolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Procedural pain:

Browse all the conditions that are associated with Procedural pain:


How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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