Prolia and Death - a phase IV clinical study of FDA data

Summary:

Death is found among people who take Prolia, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study is created by eHealthMe based on reports of 137,760 people who have side effects when taking Prolia from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 30, 2023

137,760 people reported to have side effects when taking Prolia.
Among them, 14,914 people (10.83%) died.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 138,346 Prolia users for its effectiveness, alternative drugs and more.

Number of Prolia and Death reports submitted per year:

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Expand to all the drugs that have ingredients of denosumab:

Death and drugs with ingredients of denosumab (19,013 reports)

Alternative drugs to, pros and cons of Prolia:

Prolia (138,346 reports)

Common Prolia side effects:

Death: 14,914 reports
Joint pain: 7,005 reports
Back pain: 5,503 reports
Pain: 5,270 reports
Rashes (redness): 4,215 reports
Muscle aches (muscle pain): 3,594 reports

Browse all side effects of Prolia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

COVID vaccines that are related to Death:

Common drugs associated with Death:

All the drugs that are associated with Death:

Death (4,508 drugs)

Common conditions associated with Death:

Multiple myeloma: 23,142 reports
Pain: 20,012 reports
Primary pulmonary hypertension: 17,771 reports

All the conditions that are associated with Death:

Death (3,693 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on denosumab (the active ingredients of Prolia) and Prolia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.