Prolia and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Prolia (denosumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Prolia. It is created by eHealthMe based on reports of 150,727 people who have side effects when taking Prolia from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,568 drugs and 1,602 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Apr, 15, 2026

150,727 people reported to have side effects when taking Prolia.
Among them, 201 people (0.13%) have Thyroid function test abnormal.

Could Prolia cause Thyroid function test abnormal?

Among these 201 people:

How long have people been on Prolia when they have Thyroid function test abnormal? *

What is the gender of people who have Thyroid function test abnormal when taking Prolia? *

female: 95.26 %
male: 4.74 %

What is the age of people who have Thyroid function test abnormal when taking Prolia? *

What are other drugs people take besides Prolia? *

What are other side effects people have besides Thyroid function test abnormal? *

Pain: 25 people, 12.44%
Fatigue (feeling of tiredness): 25 people, 12.44%
High Blood Pressure: 24 people, 11.94%
Weakness: 22 people, 10.95%
Pain In Extremity: 21 people, 10.45%
Diarrhea: 21 people, 10.45%
Weight Decreased: 20 people, 9.95%
Joint Pain: 20 people, 9.95%
Dizziness: 18 people, 8.96%
Hair Loss: 16 people, 7.96%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 7.46%
High Blood Cholesterol: 12 people, 5.97%
High Blood Pressure: 9 people, 4.48%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 4.48%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 2.49%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 1.99%
Malignant Melanoma (skin cancer rises from melancytes): 4 people, 1.99%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 1.99%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 1.99%
Essential Thrombocythaemia (chronic blood cancer): 3 people, 1.49%

* Approximation only. Some reports may have incomplete information.

Do you take Prolia and have Thyroid function test abnormal?

- Check whether Thyroid function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prolia:

Prolia (151,388 reports)

Browse all side effects of Prolia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,568 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,602 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on denosumab (the active ingredients of Prolia) and Prolia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.