Prolia and Visual field defect - a phase IV clinical study of FDA data

Summary:

Visual field defect is reported as a side effect among people who take Prolia (denosumab), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Crestor, and have Psoriasis.

The phase IV clinical study analyzes which people have Visual field defect when taking Prolia. It is created by eHealthMe based on reports of 150,727 people who have side effects when taking Prolia from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

What is Visual field defect?

Visual field defect is found to be associated with 766 drugs and 1,038 conditions by eHealthMe. Check the latest studies of Visual field defect.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

150,727 people reported to have side effects when taking Prolia.
Among them, 22 people (0.01%) have Visual field defect.

Among these 22 people:

How long have people been on Prolia when they have Visual field defect? *

What is the gender of people who have Visual field defect when taking Prolia? *

female: 95.45 %
male: 4.55 %

What is the age of people who have Visual field defect when taking Prolia? *

What are other drugs people take besides Prolia? *

What are other side effects people have besides Visual field defect? *

Visual Impairment: 7 people, 31.82%
Joint Pain: 5 people, 22.73%
Speech Impairment (Adult) (inability to speak (adult)): 4 people, 18.18%
Vision Blurred: 4 people, 18.18%
Drug Intolerance (drug sensitivity): 4 people, 18.18%
Pain In Extremity: 4 people, 18.18%
Chest Pain: 4 people, 18.18%
Facial Paralysis (loss of function of face muscle): 4 people, 18.18%
Hypotension (abnormally low blood pressure): 4 people, 18.18%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 13.64%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 4 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 2 people, 9.09%
Pain: 2 people, 9.09%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 9.09%
Colitis (inflammation of colon): 2 people, 9.09%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 9.09%
Tachyphrenia (abnormally rapid mental activity): 1 person, 4.55%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.55%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Prolia and have Visual field defect?

- Check whether Visual field defect is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prolia:

Prolia (151,388 reports)

Browse all side effects of Prolia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Visual field defect:

Visual field defect (766 drugs)

Browse all the conditions that are associated with Visual field defect:

Visual field defect (1,038 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on denosumab (the active ingredients of Prolia) and Prolia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.