Promacta and Bone marrow failure - a phase IV clinical study of FDA data

Summary:

Bone marrow failure is reported as a side effect among people who take Promacta (eltrombopag olamine), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Claritin, and have Idiopathic thrombocytopenic purpura.

The phase IV clinical study analyzes which people have Bone marrow failure when taking Promacta. It is created by eHealthMe based on reports of 17,717 people who have side effects when taking Promacta from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Bone marrow failure?

Bone marrow failure is found to be associated with 1,008 drugs and 1,438 conditions by eHealthMe. Check the latest studies of Bone marrow failure.

On Aug, 05, 2026

17,717 people reported to have side effects when taking Promacta.
Among them, 18 people (0.1%) have Bone marrow failure.

Could Promacta cause Bone marrow failure?

Among these 18 people:

How long have people been on Promacta when they have Bone marrow failure? *

What is the gender of people who have Bone marrow failure when taking Promacta? *

female: 50 %
male: 50 %

What is the age of people who have Bone marrow failure when taking Promacta? *

What are other drugs people take besides Promacta? *

What are other side effects people have besides Bone marrow failure? *

Thrombocytopenia (decrease of platelets in blood): 6 people, 33.33%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 27.78%
Anaemia (lack of blood): 5 people, 27.78%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 22.22%
Weight Decreased: 4 people, 22.22%
Pain: 4 people, 22.22%
Bone Marrow Reticulin Fibrosis (thickening and scarring of bone marrow reticulin): 4 people, 22.22%
Fatigue (feeling of tiredness): 3 people, 16.67%
Drug Ineffective: 2 people, 11.11%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 11.11%

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 6 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 3 people, 16.67%
Nausea (feeling of having an urge to vomit): 1 person, 5.56%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 5.56%
Leukaemia (blood or bone marrow cancer): 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 5.56%
Essential Hypertension (primary hypertension): 1 person, 5.56%
Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 5.56%
Adverse Event: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Promacta and have Bone marrow failure?

- Check whether Bone marrow failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Promacta:

Promacta (17,758 reports)

Browse all side effects of Promacta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow failure:

Bone marrow failure (1,008 drugs)

Browse all the conditions that are associated with Bone marrow failure:

Bone marrow failure (1,438 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eltrombopag olamine (the active ingredients of Promacta) and Promacta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.