Promethazine dm and Sinus congestion - a phase IV clinical study of FDA data

Summary:

Sinus congestion is reported as a side effect among people who take Promethazine dm (dextromethorphan hydrobromide; promethazine hydrochloride), especially for people who are female, 50-59 old, also take Levaquin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Sinus congestion when taking Promethazine dm. It is created by eHealthMe based on reports of 575 people who have side effects when taking Promethazine dm from the FDA, and is updated regularly.

What is Promethazine dm?

Promethazine dm has active ingredients of dextromethorphan hydrobromide; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 624 Promethazine dm users. Check the latest studies of Promethazine dm.

What is Sinus congestion?

Sinus congestion (blockage of sinus) is found to be associated with 1,004 drugs and 955 conditions by eHealthMe. Check the latest studies of Sinus congestion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

575 people reported to have side effects when taking Promethazine dm.
Among them, 12 people (2.09%) have Sinus congestion.

Could Promethazine dm cause Sinus congestion?

Among these 12 people:

What is the gender of people who have Sinus congestion when taking Promethazine dm? *

female: 100 %
male: 0.0 %

What is the age of people who have Sinus congestion when taking Promethazine dm? *

What are other drugs people take besides Promethazine dm? *

What are other side effects people have besides Sinus congestion? *

Nausea (feeling of having an urge to vomit): 12 people, 100.00%
Mucosal Inflammation (infection of mucous membrane): 12 people, 100.00%
Pain In Jaw: 12 people, 100.00%
Pain: 12 people, 100.00%
Osteoporosis (bones weak and more likely to break): 12 people, 100.00%
Osteopenia (a condition where bone mineral density is lower than normal): 12 people, 100.00%
Neuropathy Peripheral (surface nerve damage): 12 people, 100.00%
Nausea And Vomiting: 12 people, 100.00%
Ear Pain: 12 people, 100.00%
Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 12 people, 100.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Promethazine dm and have Sinus congestion?

- Check whether Sinus congestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Promethazine dm:

Promethazine dm (624 reports)

Sinus congestion treatments and more:

Sinus congestion (21,241 reports)

How severe was Sinus congestion and when was it recovered:

Sinus congestion in Promethazine dm

Expand to all the drugs that have ingredients of dextromethorphan hydrobromide; promethazine hydrochloride:

Sinus congestion and drugs with ingredients of dextromethorphan hydrobromide; promethazine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Promethazine dm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus congestion:

Sinus congestion (1,005 drugs)

Browse all the conditions that are associated with Sinus congestion:

Sinus congestion (955 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dextromethorphan hydrobromide; promethazine hydrochloride (the active ingredients of Promethazine dm) and Promethazine dm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.