Propacet 100 and Coronary heart disease - a phase IV clinical study of FDA data

Summary:

Coronary heart disease is reported as a side effect among people who take Propacet 100 (acetaminophen; propoxyphene napsylate), especially for people who are male, 40-49 old, also take Vioxx, and have Pain.

The phase IV clinical study analyzes which people have Coronary heart disease when taking Propacet 100. It is created by eHealthMe based on reports of 1,280 people who have side effects when taking Propacet 100 from the FDA, and is updated regularly.

What is Propacet 100?

Propacet 100 has active ingredients of acetaminophen; propoxyphene napsylate. eHealthMe is studying from 1,282 Propacet 100 users. Check the latest studies of Propacet 100.

What is Coronary heart disease?

Coronary heart disease (narrowing or blockage of the coronary arteries) is found to be associated with 1,598 drugs and 2,171 conditions by eHealthMe. Check the latest studies of Coronary heart disease.

On Jul, 05, 2026

1,280 people reported to have side effects when taking Propacet 100.
Among them, 22 people (1.72%) have Coronary heart disease.

Could Propacet 100 cause Coronary heart disease?

Among these 22 people:

What is the gender of people who have Coronary heart disease when taking Propacet 100? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Coronary heart disease when taking Propacet 100? *

What are other drugs people take besides Propacet 100? *

What are other side effects people have besides Coronary heart disease? *

High Blood Pressure: 19 people, 86.36%
Stress And Anxiety: 18 people, 81.82%
Stable Angina (a constant chest pain): 18 people, 81.82%
Chest Pain: 17 people, 77.27%
Cardiac Failure Congestive: 16 people, 72.73%
Dyspnea (difficult or laboured breathing): 16 people, 72.73%
Hypersensitivity: 15 people, 68.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 68.18%
Hyperlipidaemia (presence of excess lipids in the blood): 15 people, 68.18%
Cardiac Disorder: 15 people, 68.18%

What are the existing conditions these people have? *

Pain: 16 people, 72.73%
Neck Pain: 14 people, 63.64%
Joint Pain: 2 people, 9.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.55%
High Blood Pressure: 1 person, 4.55%
High Blood Cholesterol: 1 person, 4.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.55%
Gastric Disorder (disease of stomach): 1 person, 4.55%
Chest Pain: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Propacet 100 and have Coronary heart disease?

- Check whether Coronary heart disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propacet 100:

Propacet 100 (1,282 reports)

Coronary heart disease treatments and more:

Coronary heart disease (70,508 reports)

How severe was Coronary heart disease and when was it recovered:

Coronary heart disease in Propacet 100

Expand to all the drugs that have ingredients of acetaminophen; propoxyphene napsylate:

Coronary heart disease and drugs with ingredients of acetaminophen; propoxyphene napsylate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propacet 100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coronary heart disease:

Coronary heart disease (1,598 drugs)

Browse all the conditions that are associated with Coronary heart disease:

Coronary heart disease (2,171 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; propoxyphene napsylate (the active ingredients of Propacet 100) and Propacet 100 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.