Propecia and Hypogonadotropic hypogonadism - a phase IV clinical study of FDA data

Summary:

Hypogonadotropic hypogonadism is reported as a side effect among people who take Propecia (finasteride), especially for people who are male, 40-49 old, have been taking the drug for 10+ years also take Proscar, and have Androgenetic alopecia.

The phase IV clinical study analyzes which people have Hypogonadotropic hypogonadism when taking Propecia. It is created by eHealthMe based on reports of 9,411 people who have side effects when taking Propecia from the FDA, and is updated regularly.

What is Propecia?

Propecia has active ingredients of finasteride. It is often used in hair loss. eHealthMe is studying from 9,757 Propecia users. Check the latest studies of Propecia.

What is Hypogonadotropic hypogonadism?

Hypogonadotropic hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries) due to a problem with the pituitary gland or hypothalamus) is found to be associated with 46 drugs and 180 conditions by eHealthMe. Check the latest studies of Hypogonadotropic hypogonadism.



On Jul, 20, 2026

9,411 people reported to have side effects when taking Propecia.
Among them, 43 people (0.46%) have Hypogonadotropic hypogonadism.

Could Propecia cause Hypogonadotropic hypogonadism?

Among these 43 people:

How long have people been on Propecia when they have Hypogonadotropic hypogonadism? *

  • < 1 month: 5.56 %
  • 1 - 6 months: 8.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 13.89 %
  • 10+ years: 30.56 %

What is the gender of people who have Hypogonadotropic hypogonadism when taking Propecia? *

  • female: 2.33 %
  • male: 97.67 %

What is the age of people who have Hypogonadotropic hypogonadism when taking Propecia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.25 %
  • 30-39: 0.0 %
  • 40-49: 75.0 %
  • 50-59: 12.5 %
  • 60+: 6.25 %

What are other drugs people take besides Propecia? *

  1. Proscar: 18 people, 41.86%
  2. Coumadin: 2 people, 4.65%
  3. Prilosec: 2 people, 4.65%
  4. Finasteride: 2 people, 4.65%
  5. Warfarin Sodium: 1 person, 2.33%
  6. Furosemide: 1 person, 2.33%
  7. Alprazolam: 1 person, 2.33%
  8. Crestor: 1 person, 2.33%
  9. Dexedrine: 1 person, 2.33%
  10. Dofetilide: 1 person, 2.33%

What are other side effects people have besides Hypogonadotropic hypogonadism? *

  1. Erection Problems: 42 people, 97.67%
  2. Depression: 31 people, 72.09%
  3. Weight Increased: 24 people, 55.81%
  4. Libido Decreased (loss of interest in sex): 24 people, 55.81%
  5. High Blood Pressure: 23 people, 53.49%
  6. Blood Testosterone Decreased: 22 people, 51.16%
  7. Back Pain: 22 people, 51.16%
  8. Stress And Anxiety: 22 people, 51.16%
  9. Fatigue (feeling of tiredness): 20 people, 46.51%
  10. Loss Of Libido (loss of sexual urge): 19 people, 44.19%

What are the existing conditions these people have? *

  1. Androgenetic Alopecia (common form of hair loss): 16 people, 37.21%
  2. Enlarged Prostate: 4 people, 9.30%
  3. High Blood Pressure: 2 people, 4.65%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.65%
  5. Depression: 2 people, 4.65%
  6. Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 2.33%
  7. Oral Herpes (viral infection of mouth): 1 person, 2.33%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 2.33%
  9. Bipolar Disorder (mood disorder): 1 person, 2.33%
  10. Alopecia Areata (patchy baldness that typically begins with rapid hair loss): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Propecia and have Hypogonadotropic hypogonadism?

- Check whether Hypogonadotropic hypogonadism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propecia:

Hypogonadotropic hypogonadism treatments and more:

How severe was Hypogonadotropic hypogonadism and when was it recovered:

Expand to all the drugs that have ingredients of finasteride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propecia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypogonadotropic hypogonadism:

Browse all the conditions that are associated with Hypogonadotropic hypogonadism:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on finasteride (the active ingredients of Propecia) and Propecia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: