Propranolol hydrochloride and Initial insomnia - a phase IV clinical study of FDA data

Summary:

Initial insomnia is reported as a side effect among people who take Propranolol hydrochloride (propranolol hydrochloride), especially for people who are female, 50-59 old, also take Lyrica, and have Cataplexy.

The phase IV clinical study analyzes which people have Initial insomnia when taking Propranolol hydrochloride. It is created by eHealthMe based on reports of 9,728 people who have side effects when taking Propranolol hydrochloride from the FDA, and is updated regularly.

What is Propranolol hydrochloride?

Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 12,026 Propranolol hydrochloride users. Check the latest studies of Propranolol hydrochloride.

What is Initial insomnia?

Initial insomnia (feeling of inadequate or poor-quality sleep) is found to be associated with 713 drugs and 690 conditions by eHealthMe. Check the latest studies of Initial insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

9,728 people reported to have side effects when taking Propranolol hydrochloride.
Among them, 12 people (0.12%) have Initial insomnia.

Could Propranolol hydrochloride cause Initial insomnia?

Among these 12 people:

What is the gender of people who have Initial insomnia when taking Propranolol hydrochloride? *

female: 80 %
male: 20 %

What is the age of people who have Initial insomnia when taking Propranolol hydrochloride? *

What are other drugs people take besides Propranolol hydrochloride? *

What are other side effects people have besides Initial insomnia? *

Nausea And Vomiting: 6 people, 50.00%
Dry Mouth: 6 people, 50.00%
Hyperhidrosis (abnormally increased sweating): 5 people, 41.67%
Drowsiness: 4 people, 33.33%
Dyspnea (difficult or laboured breathing): 4 people, 33.33%
Dizziness: 4 people, 33.33%
Insomnia (sleeplessness): 4 people, 33.33%
Laboratory Test Abnormal: 3 people, 25.00%
Weakness: 3 people, 25.00%
Hallucination, Visual (seeing things that aren't there): 3 people, 25.00%

What are the existing conditions these people have? *

Pain: 3 people, 25.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
Fallopian Tube Cancer (cancer of fallopian tube): 3 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 25.00%
Weakness: 1 person, 8.33%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 8.33%
Pain In Extremity: 1 person, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Joint Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Propranolol hydrochloride and have Initial insomnia?

- Check whether Initial insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propranolol hydrochloride:

Propranolol hydrochloride (12,026 reports)

Initial insomnia treatments and more:

Initial insomnia (12,139 reports)

Browse all side effects of Propranolol hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Initial insomnia:

Initial insomnia (713 drugs)

Browse all the conditions that are associated with Initial insomnia:

Initial insomnia (690 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on propranolol hydrochloride (the active ingredients of Propranolol hydrochloride) and Propranolol hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.