Propulsid and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Propulsid (cisapride monohydrate), especially for people who are female, 40-49 old, also take Prilosec, and have Heart palpitations.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Propulsid. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Propulsid from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 977 drugs and 1,437 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.



On Jul, 20, 2026

8,120 people reported to have side effects when taking Propulsid.
Among them, 13 people (0.16%) have Hyperthyroidism.

Could Propulsid cause Hyperthyroidism?

Among these 13 people:

What is the gender of people who have Hyperthyroidism when taking Propulsid? *

  • female: 84.62 %
  • male: 15.38 %

What is the age of people who have Hyperthyroidism when taking Propulsid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 66.67 %
  • 50-59: 16.67 %
  • 60+: 16.67 %

What are other drugs people take besides Propulsid? *

  1. Prilosec: 8 people, 61.54%
  2. Ativan: 7 people, 53.85%
  3. Naproxen: 6 people, 46.15%
  4. Hydrochlorothiazide: 6 people, 46.15%
  5. Zantac: 6 people, 46.15%
  6. Carafate: 6 people, 46.15%
  7. Amoxil: 6 people, 46.15%
  8. Atenolol: 6 people, 46.15%
  9. Procardia: 5 people, 38.46%
  10. Reglan: 5 people, 38.46%

What are other side effects people have besides Hyperthyroidism? *

  1. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 84.62%
  2. Chest Pain: 7 people, 53.85%
  3. Dyspnea Exertional: 7 people, 53.85%
  4. Throat Irritation: 6 people, 46.15%
  5. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 46.15%
  6. Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 6 people, 46.15%
  7. Hyperventilation: 6 people, 46.15%
  8. Hypoaesthesia (reduced sense of touch or sensation): 6 people, 46.15%
  9. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 5 people, 38.46%
  10. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 5 people, 38.46%

What are the existing conditions these people have? *

  1. Impaired Gastric Emptying: 1 person, 7.69%
  2. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Propulsid and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propulsid:

Hyperthyroidism treatments and more:

How severe was Hyperthyroidism and when was it recovered:

Expand to all the drugs that have ingredients of cisapride monohydrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Browse all the conditions that are associated with Hyperthyroidism:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cisapride monohydrate (the active ingredients of Propulsid) and Propulsid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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