Propulsid and Suicidal ideation - a phase IV clinical study of FDA data

Summary:

Suicidal ideation is reported as a side effect among people who take Propulsid (cisapride monohydrate), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Prilosec, and have Gastrointestinal motility disorder.

The phase IV clinical study analyzes which people have Suicidal ideation when taking Propulsid. It is created by eHealthMe based on reports of 8,120 people who have side effects when taking Propulsid from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Suicidal ideation?

Suicidal ideation is found to be associated with 1,978 drugs and 2,343 conditions by eHealthMe. Check the latest studies of Suicidal ideation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

8,120 people reported to have side effects when taking Propulsid.
Among them, 19 people (0.23%) have Suicidal ideation.

Could Propulsid cause Suicidal ideation?

Among these 19 people:

How long have people been on Propulsid when they have Suicidal ideation? *

What is the gender of people who have Suicidal ideation when taking Propulsid? *

female: 73.68 %
male: 26.32 %

What is the age of people who have Suicidal ideation when taking Propulsid? *

What are other drugs people take besides Propulsid? *

What are other side effects people have besides Suicidal ideation? *

Constipation: 7 people, 36.84%
Back Pain: 6 people, 31.58%
Chest Pain: 5 people, 26.32%
Weight Decreased: 5 people, 26.32%
Fever: 5 people, 26.32%
Muscle Aches (muscle pain): 4 people, 21.05%
Weakness: 4 people, 21.05%
Neck Pain: 4 people, 21.05%
Nausea (feeling of having an urge to vomit): 4 people, 21.05%
Rectal Bleeding (bleeding from rectum): 4 people, 21.05%

What are the existing conditions these people have? *

Gastrointestinal Motility Disorder (abnormal intestinal contractions): 3 people, 15.79%
Migraine (headache): 2 people, 10.53%
Vaginal Bleeding Between Periods: 1 person, 5.26%
Back Pain: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Propulsid and have Suicidal ideation?

- Check whether Suicidal ideation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propulsid:

Propulsid (8,130 reports)

Suicidal ideation treatments and more:

Suicidal ideation (109,012 reports)

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Suicidal ideation:

Suicidal ideation (1,978 drugs)

Browse all the conditions that are associated with Suicidal ideation:

Suicidal ideation (2,343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cisapride monohydrate (the active ingredients of Propulsid) and Propulsid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.