Propylthiouracil and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Propylthiouracil (propylthiouracil), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Nexium, and have Flatulence.

The study is created by eHealthMe based on reports of 2,435 people who have side effects when taking Propylthiouracil from the FDA, and is updated regularly.

What is Propylthiouracil?

Propylthiouracil has active ingredients of propylthiouracil. It is often used in hyperthyroidism. eHealthMe is studying from 2,545 Propylthiouracil users. Check the latest studies of Propylthiouracil.

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On Sep, 01, 2026

2,435 people reported to have side effects when taking Propylthiouracil.
Among them, 28 people (1.15%) died.

Among these 28 people:

How long have people been on Propylthiouracil when they died? *

What is the gender of people who died when taking Propylthiouracil? *

female: 77.78 %
male: 22.22 %

What is the age of people who died when taking Propylthiouracil? *

What are other drugs people take besides Propylthiouracil? *

Nexium: 6 people, 21.43%
Amlodipine: 5 people, 17.86%
Ondansetron: 5 people, 17.86%
Prednisone: 4 people, 14.29%
Metformin: 4 people, 14.29%
Hydrocodone Bitartrate And Acetaminophen: 4 people, 14.29%
Protonix: 4 people, 14.29%
Cytoxan: 3 people, 10.71%
Prevacid: 3 people, 10.71%
Lipitor: 3 people, 10.71%

What are other side effects people have before they died? *

Acute Kidney Failure: 5 people, 17.86%
Cardiac Failure Congestive: 5 people, 17.86%
Heart Disease: 4 people, 14.29%
Depression: 4 people, 14.29%
Chronic Kidney Disease: 4 people, 14.29%
Nausea (feeling of having an urge to vomit): 4 people, 14.29%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 14.29%
Weight Decreased: 3 people, 10.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 10.71%
Fatigue (feeling of tiredness): 3 people, 10.71%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 3 people, 10.71%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 10.71%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 10.71%
Constipation: 3 people, 10.71%
Flatulence (flatus expelled through the anus): 3 people, 10.71%
Bipolar Disorder (mood disorder): 2 people, 7.14%
Cardiac Failure: 2 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.14%
Thyrotoxic Crisis (a life threatening condition due to excess secretion of thyroid hormone): 2 people, 7.14%
Cervix Carcinoma (cancer of cervix): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Propylthiouracil:

Propylthiouracil (2,545 reports)

Expand to all the drugs that have ingredients of propylthiouracil:

Death and drugs with ingredients of propylthiouracil

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propylthiouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,107 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

Related publications that referenced our studies

Ayturk S, Demir MV, Yaylac? S, Tamer A, "Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation", Indian journal of endocrinology and metabolism, 2013 Jan .
Ayturk S, Demir MV, Yaylac? S, Tamer A, "Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation", Indian journal of endocrinology and metabolism, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on propylthiouracil (the active ingredients of Propylthiouracil) and Propylthiouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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