Protonix and Gallbladder non-functioning - a phase IV clinical study of FDA data

Summary:

Gallbladder non-functioning is reported as a side effect among people who take Protonix (pantoprazole sodium), especially for people who are female, 30-39 old, also take Yaz, and have Birth control.

The phase IV clinical study analyzes which people have Gallbladder non-functioning when taking Protonix. It is created by eHealthMe based on reports of 130,073 people who have side effects when taking Protonix from the FDA, and is updated regularly.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,653 Protonix users. Check the latest studies of Protonix.

What is Gallbladder non-functioning?

Gallbladder non-functioning is found to be associated with 138 drugs and 439 conditions by eHealthMe. Check the latest studies of Gallbladder non-functioning.

On Nov, 21, 2025

130,073 people reported to have side effects when taking Protonix.
Among them, 45 people (0.03%) have Gallbladder non-functioning.

Could Protonix cause Gallbladder non-functioning?

Among these 45 people:

What is the gender of people who have Gallbladder non-functioning when taking Protonix? *

female: 91.11 %
male: 8.89 %

What is the age of people who have Gallbladder non-functioning when taking Protonix? *

What are other drugs people take besides Protonix? *

Yaz: 30 people, 66.67%
Yasmin: 25 people, 55.56%
Ibuprofen: 8 people, 17.78%
Allegra: 7 people, 15.56%
Prilosec: 6 people, 13.33%
Drospirenone And Ethinyl Estradiol: 6 people, 13.33%
Prevacid: 6 people, 13.33%
Synthroid: 5 people, 11.11%
Pepcid: 5 people, 11.11%
Macrobid: 4 people, 8.89%

What are other side effects people have besides Gallbladder non-functioning? *

Cholecystitis Chronic (long lasting infection of gallbladder): 25 people, 55.56%
Pain: 24 people, 53.33%
Injury: 13 people, 28.89%
Stress And Anxiety: 13 people, 28.89%
Gallstones (stone formation by bile component): 12 people, 26.67%
Biliary Dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi): 11 people, 24.44%
Nausea (feeling of having an urge to vomit): 11 people, 24.44%
Abdominal Pain: 11 people, 24.44%
Organ Failure: 10 people, 22.22%
Nausea And Vomiting: 7 people, 15.56%

What are the existing conditions these people have? *

Birth Control: 15 people, 33.33%
Migraine (headache): 8 people, 17.78%
Acne (skin problems that cause pimples): 5 people, 11.11%
Pain: 5 people, 11.11%
Urinary Tract Infection: 4 people, 8.89%
Multiple Allergies (allergy to multiple agents): 4 people, 8.89%
Premenstrual Syndrome: 4 people, 8.89%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.89%
High Blood Cholesterol: 3 people, 6.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Protonix and have Gallbladder non-functioning?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Protonix:

Protonix (132,653 reports)

Browse all side effects of Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder non-functioning:

Gallbladder non-functioning (138 drugs)

Browse all the conditions that are associated with Gallbladder non-functioning:

Gallbladder non-functioning (439 conditions)

Drugs similar to Protonix and Gallbladder non-functioning :

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium (the active ingredients of Protonix) and Protonix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.