Protopic and Hernia - a phase IV clinical study of FDA data

Summary:

Hernia is reported as a side effect among people who take Protopic (tacrolimus), especially for people who are male, 60+ old, also take Prevacid, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Hernia when taking Protopic. It is created by eHealthMe based on reports of 5,328 people who have side effects when taking Protopic from the FDA, and is updated regularly.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

What is Hernia?

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle) is found to be associated with 1,365 drugs and 1,486 conditions by eHealthMe. Check the latest studies of Hernia.

On Feb, 13, 2026

5,328 people reported to have side effects when taking Protopic.
Among them, 20 people (0.38%) have Hernia.

Among these 20 people:

What is the gender of people who have Hernia when taking Protopic? *

female: 50 %
male: 50 %

What is the age of people who have Hernia when taking Protopic? *

What are other drugs people take besides Protopic? *

What are other side effects people have besides Hernia? *

Back Pain: 11 people, 55.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 40.00%
Joint Pain: 7 people, 35.00%
High Blood Pressure: 7 people, 35.00%
Muscle Aches (muscle pain): 7 people, 35.00%
Weakness: 7 people, 35.00%
Joint Range Of Motion Decreased (disease of joint movement): 6 people, 30.00%
Irritable Bowel Syndrome: 6 people, 30.00%
Iron Deficiency: 6 people, 30.00%
Weight Loss: 6 people, 30.00%

What are the existing conditions these people have? *

High Blood Cholesterol: 6 people, 30.00%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 3 people, 15.00%
Pleural Effusion (water on the lungs): 3 people, 15.00%
Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 3 people, 15.00%
Oedema Peripheral (superficial swelling): 3 people, 15.00%
Nail Abnormalities (abnormal nail): 3 people, 15.00%
Multiple Myeloma (cancer of the plasma cells): 3 people, 15.00%
Diarrhea: 3 people, 15.00%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 3 people, 15.00%
Skin Reaction: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Protopic and have Hernia?

- Check whether Hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Protopic:

Protopic (5,403 reports)

Hernia treatments and more:

Hernia (31,430 reports)

Browse all side effects of Protopic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hernia:

Hernia (1,365 drugs)

Browse all the conditions that are associated with Hernia:

Hernia (1,486 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Protopic) and Protopic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.