Protopic and Psoriatic arthropathy aggravated - a phase IV clinical study of FDA data

Summary:

Psoriatic arthropathy aggravated is reported as a side effect among people who take Protopic (tacrolimus), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Cosentyx, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Psoriatic arthropathy aggravated when taking Protopic. It is created by eHealthMe based on reports of 5,328 people who have side effects when taking Protopic from the FDA, and is updated regularly.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

What is Psoriatic arthropathy aggravated?

Psoriatic arthropathy aggravated (serious inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop) is found to be associated with 788 drugs and 281 conditions by eHealthMe. Check the latest studies of Psoriatic arthropathy aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

5,328 people reported to have side effects when taking Protopic.
Among them, 88 people (1.65%) have Psoriatic arthropathy aggravated.

Could Protopic cause Psoriatic arthropathy aggravated?

Among these 88 people:

How long have people been on Protopic when they have Psoriatic arthropathy aggravated? *

What is the gender of people who have Psoriatic arthropathy aggravated when taking Protopic? *

female: 57.32 %
male: 42.68 %

What is the age of people who have Psoriatic arthropathy aggravated when taking Protopic? *

What are other drugs people take besides Protopic? *

What are other side effects people have besides Psoriatic arthropathy aggravated? *

Peripheral Swelling: 37 people, 42.05%
Fatigue (feeling of tiredness): 32 people, 36.36%
Pain: 31 people, 35.23%
Nasopharyngitis (inflammation of the nasopharynx): 24 people, 27.27%
Joint Pain: 23 people, 26.14%
Drug Ineffective: 21 people, 23.86%
Depression: 21 people, 23.86%
Stress And Anxiety: 20 people, 22.73%
Pain In Extremity: 19 people, 21.59%
Gait Disturbance: 19 people, 21.59%

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 6 people, 6.82%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 6 people, 6.82%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 5.68%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 4.55%
Hypersensitivity: 3 people, 3.41%
High Blood Pressure: 3 people, 3.41%
Sleep Disorder: 2 people, 2.27%
Blepharitis (chronic inflammation of the eyelid): 2 people, 2.27%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 2.27%
Cough: 2 people, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Protopic and have Psoriatic arthropathy aggravated?

- Check whether Psoriatic arthropathy aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Protopic:

Protopic (5,403 reports)

Browse all side effects of Protopic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psoriatic arthropathy aggravated:

Psoriatic arthropathy aggravated (788 drugs)

Browse all the conditions that are associated with Psoriatic arthropathy aggravated:

Psoriatic arthropathy aggravated (281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Protopic) and Protopic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.