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Protopic and Sinus congestion - a phase IV clinical study of FDA data

Summary:

Sinus congestion is reported as a side effect among people who take Protopic (tacrolimus), especially for people who are female, 60+ old, also take Calcipotriene And Betamethasone Dipropionate, and have Dermatitis atopic.

The phase IV clinical study analyzes which people have Sinus congestion when taking Protopic. It is created by eHealthMe based on reports of 5,328 people who have side effects when taking Protopic from the FDA, and is updated regularly.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

What is Sinus congestion?

Sinus congestion (blockage of sinus) is found to be associated with 1,006 drugs and 954 conditions by eHealthMe. Check the latest studies of Sinus congestion.

On Jul, 18, 2026

5,328 people reported to have side effects when taking Protopic.
Among them, 14 people (0.26%) have Sinus congestion.

Could Protopic cause Sinus congestion?

Among these 14 people:

What is the gender of people who have Sinus congestion when taking Protopic? *

  • female: 85.71 %
  • male: 14.29 %

What is the age of people who have Sinus congestion when taking Protopic? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.14 %
  • 20-29: 7.14 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 0.0 %
  • 60+: 78.57 %

What are other drugs people take besides Protopic? *

  1. Humira: 7 people, 50.00%
  2. Cosentyx: 7 people, 50.00%
  3. Calcipotriene And Betamethasone Dipropionate: 7 people, 50.00%
  4. Aspirin: 4 people, 28.57%
  5. Calcitriol: 3 people, 21.43%
  6. Sertraline: 3 people, 21.43%
  7. Methotrexate: 3 people, 21.43%
  8. Acitretin: 3 people, 21.43%
  9. Prednisone: 3 people, 21.43%
  10. Clobetasol Propionate: 2 people, 14.29%

What are other side effects people have besides Sinus congestion? *

  1. Fever: 10 people, 71.43%
  2. Diarrhea: 9 people, 64.29%
  3. Asthma: 9 people, 64.29%
  4. Chills (felling of cold): 9 people, 64.29%
  5. Skin Blushing/flushing (a sudden reddening of the face, neck): 9 people, 64.29%
  6. Fatigue (feeling of tiredness): 9 people, 64.29%
  7. Cough: 8 people, 57.14%
  8. Fungal Infection: 7 people, 50.00%
  9. Viral Infection: 7 people, 50.00%
  10. Nasopharyngitis (inflammation of the nasopharynx): 7 people, 50.00%

What are the existing conditions these people have? *

  1. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 21.43%
  2. Immunodeficiency Common Variable: 2 people, 14.29%
  3. Depression: 2 people, 14.29%
  4. Hypersensitivity: 1 person, 7.14%
  5. Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 1 person, 7.14%
  6. Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Protopic and have Sinus congestion?

- Check whether Sinus congestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Protopic:

Sinus congestion treatments and more:

How severe was Sinus congestion and when was it recovered:

Expand to all the drugs that have ingredients of tacrolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Protopic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus congestion:

Browse all the conditions that are associated with Sinus congestion:

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Protopic) and Protopic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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